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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHYH All Species: 28.48
Human Site: T119 Identified Species: 62.67
UniProt: O14832 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14832 NP_006205.1 338 38538 T119 A P S E K M I T K V Q D F Q E
Chimpanzee Pan troglodytes XP_507662 338 38544 T119 A P S E K M I T K V Q D F Q E
Rhesus Macaque Macaca mulatta XP_001085862 338 38670 T119 T P S E K M T T K V Q D F Q E
Dog Lupus familis XP_535184 540 60291 S321 I P S E R M I S K I Q D F Q E
Cat Felis silvestris
Mouse Mus musculus O35386 338 38589 S119 M P S D R M V S K I Q D F Q E
Rat Rattus norvegicus P57093 338 38570 T119 A P S E R V V T K I Q D F Q Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_424238 289 33402 R83 V S D E D I E R F R K E F I R
Frog Xenopus laevis NP_001086497 334 38166 T116 V P D Q K A I T K L Q D F Q E
Zebra Danio Brachydanio rerio NP_001017823 335 38486 T116 V E G E K A V T K L Q D Y Q E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O62515 312 35701 Q86 E K A I T K I Q D F A D D P V
Sea Urchin Strong. purpuratus XP_784265 255 28831 Y50 D N E V L F S Y C S S P E L L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 95.2 50 N.A. 78.1 78.1 N.A. N.A. 54.4 69.8 68.3 N.A. N.A. N.A. 55 49.4
Protein Similarity: 100 99.4 97.3 55.5 N.A. 87.8 89 N.A. N.A. 67.7 80.4 81.3 N.A. N.A. N.A. 71.3 61.5
P-Site Identity: 100 100 86.6 73.3 N.A. 60 66.6 N.A. N.A. 13.3 66.6 53.3 N.A. N.A. N.A. 13.3 0
P-Site Similarity: 100 100 86.6 93.3 N.A. 93.3 100 N.A. N.A. 33.3 80 73.3 N.A. N.A. N.A. 20 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 28 0 10 0 0 19 0 0 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 10 0 19 10 10 0 0 0 10 0 0 82 10 0 0 % D
% Glu: 10 10 10 64 0 0 10 0 0 0 0 10 10 0 64 % E
% Phe: 0 0 0 0 0 10 0 0 10 10 0 0 73 0 0 % F
% Gly: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 10 0 10 46 0 0 28 0 0 0 10 0 % I
% Lys: 0 10 0 0 46 10 0 0 73 0 10 0 0 0 0 % K
% Leu: 0 0 0 0 10 0 0 0 0 19 0 0 0 10 10 % L
% Met: 10 0 0 0 0 46 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 64 0 0 0 0 0 0 0 0 0 10 0 10 0 % P
% Gln: 0 0 0 10 0 0 0 10 0 0 73 0 0 73 10 % Q
% Arg: 0 0 0 0 28 0 0 10 0 10 0 0 0 0 10 % R
% Ser: 0 10 55 0 0 0 10 19 0 10 10 0 0 0 0 % S
% Thr: 10 0 0 0 10 0 10 55 0 0 0 0 0 0 0 % T
% Val: 28 0 0 10 0 10 28 0 0 28 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _