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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHYH All Species: 28.79
Human Site: T54 Identified Species: 63.33
UniProt: O14832 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14832 NP_006205.1 338 38538 T54 T L D N N V L T L E Q R K F Y
Chimpanzee Pan troglodytes XP_507662 338 38544 T54 T L D N N V L T L E Q R K F Y
Rhesus Macaque Macaca mulatta XP_001085862 338 38670 T54 T L D N N V L T L E Q R K F Y
Dog Lupus familis XP_535184 540 60291 S256 T Q H N A V L S L E Q R K F Y
Cat Felis silvestris
Mouse Mus musculus O35386 338 38589 T54 T L D N N V L T L E Q R K F Y
Rat Rattus norvegicus P57093 338 38570 S54 T L D N N V L S L E Q R K F Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_424238 289 33402 V41 T S A Q V S A V H Q P G R F R
Frog Xenopus laevis NP_001086497 334 38166 T51 T L D N N F L T R E Q R Q F Y
Zebra Danio Brachydanio rerio NP_001017823 335 38486 T51 T F D T D V L T Q E Q R I A Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O62515 312 35701 F44 P Q Y E L N R F R Q R F Q D I
Sea Urchin Strong. purpuratus XP_784265 255 28831 E8 E E F E L I C E G K N R Q R S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 95.2 50 N.A. 78.1 78.1 N.A. N.A. 54.4 69.8 68.3 N.A. N.A. N.A. 55 49.4
Protein Similarity: 100 99.4 97.3 55.5 N.A. 87.8 89 N.A. N.A. 67.7 80.4 81.3 N.A. N.A. N.A. 71.3 61.5
P-Site Identity: 100 100 100 73.3 N.A. 100 93.3 N.A. N.A. 13.3 80 60 N.A. N.A. N.A. 0 6.6
P-Site Similarity: 100 100 100 80 N.A. 100 100 N.A. N.A. 26.6 86.6 66.6 N.A. N.A. N.A. 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 10 0 10 0 0 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 64 0 10 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 10 10 0 19 0 0 0 10 0 73 0 0 0 0 0 % E
% Phe: 0 10 10 0 0 10 0 10 0 0 0 10 0 73 0 % F
% Gly: 0 0 0 0 0 0 0 0 10 0 0 10 0 0 0 % G
% His: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 10 0 0 55 0 0 % K
% Leu: 0 55 0 0 19 0 73 0 55 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 64 55 10 0 0 0 0 10 0 0 0 0 % N
% Pro: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % P
% Gln: 0 19 0 10 0 0 0 0 10 19 73 0 28 0 0 % Q
% Arg: 0 0 0 0 0 0 10 0 19 0 10 82 10 10 10 % R
% Ser: 0 10 0 0 0 10 0 19 0 0 0 0 0 0 10 % S
% Thr: 82 0 0 10 0 0 0 55 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 10 64 0 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 73 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _