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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHYH
All Species:
34.55
Human Site:
Y222
Identified Species:
76
UniProt:
O14832
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14832
NP_006205.1
338
38538
Y222
G
S
L
K
P
H
D
Y
P
K
W
E
G
G
V
Chimpanzee
Pan troglodytes
XP_507662
338
38544
Y222
G
S
L
K
P
H
D
Y
P
K
W
E
G
G
V
Rhesus Macaque
Macaca mulatta
XP_001085862
338
38670
Y222
G
S
L
K
P
H
D
Y
P
K
W
E
G
G
V
Dog
Lupus familis
XP_535184
540
60291
Y424
G
P
L
K
P
H
D
Y
P
Q
W
E
G
G
V
Cat
Felis silvestris
Mouse
Mus musculus
O35386
338
38589
Y222
G
T
L
K
P
H
D
Y
P
K
W
E
G
G
V
Rat
Rattus norvegicus
P57093
338
38570
Y222
G
P
L
K
P
H
D
Y
P
K
W
E
G
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424238
289
33402
R186
D
L
H
Y
F
P
F
R
P
A
D
R
I
V
C
Frog
Xenopus laevis
NP_001086497
334
38166
Y219
G
T
L
K
Q
H
D
Y
P
E
W
E
G
G
V
Zebra Danio
Brachydanio rerio
NP_001017823
335
38486
Y219
G
S
L
Q
E
H
D
Y
P
E
W
E
G
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O62515
312
35701
Y189
G
V
L
L
P
H
E
Y
P
K
W
E
G
G
V
Sea Urchin
Strong. purpuratus
XP_784265
255
28831
I153
V
N
K
M
Y
H
G
I
M
D
F
D
A
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
95.2
50
N.A.
78.1
78.1
N.A.
N.A.
54.4
69.8
68.3
N.A.
N.A.
N.A.
55
49.4
Protein Similarity:
100
99.4
97.3
55.5
N.A.
87.8
89
N.A.
N.A.
67.7
80.4
81.3
N.A.
N.A.
N.A.
71.3
61.5
P-Site Identity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
N.A.
6.6
80
80
N.A.
N.A.
N.A.
80
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
93.3
N.A.
N.A.
6.6
93.3
93.3
N.A.
N.A.
N.A.
86.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
10
0
0
0
0
0
73
0
0
10
10
10
0
0
0
% D
% Glu:
0
0
0
0
10
0
10
0
0
19
0
82
0
0
0
% E
% Phe:
0
0
0
0
10
0
10
0
0
0
10
0
0
0
0
% F
% Gly:
82
0
0
0
0
0
10
0
0
0
0
0
82
82
0
% G
% His:
0
0
10
0
0
91
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% I
% Lys:
0
0
10
64
0
0
0
0
0
55
0
0
0
0
0
% K
% Leu:
0
10
82
10
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
19
0
0
64
10
0
0
91
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
10
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% R
% Ser:
0
37
0
0
0
0
0
0
0
0
0
0
0
10
0
% S
% Thr:
0
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
10
0
0
0
0
0
0
0
0
0
0
0
10
82
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
82
0
0
0
0
% W
% Tyr:
0
0
0
10
10
0
0
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _