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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHYH All Species: 26.67
Human Site: Y239 Identified Species: 58.67
UniProt: O14832 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14832 NP_006205.1 338 38538 Y239 M F H G I Q D Y E E N K A R V
Chimpanzee Pan troglodytes XP_507662 338 38544 Y239 M F H G I Q D Y E E N K A R V
Rhesus Macaque Macaca mulatta XP_001085862 338 38670 Y239 M F H G I Q D Y E E N N A R V
Dog Lupus familis XP_535184 540 60291 Y441 M F Y G I Q D Y D E K T P R V
Cat Felis silvestris
Mouse Mus musculus O35386 338 38589 Y239 M Y H G I Q D Y D P N S P R V
Rat Rattus norvegicus P57093 338 38570 Y239 M Y H G I Q D Y D P D S P R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_424238 289 33402 A201 S W T A M Q R A D E N N G C L
Frog Xenopus laevis NP_001086497 334 38166 F236 M Y H G I R D F D L S I P R V
Zebra Danio Brachydanio rerio NP_001017823 335 38486 Y236 M Y H G V R N Y D P N H P R V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O62515 312 35701 Y206 A Y H G I Q D Y D T S T P R I
Sea Urchin Strong. purpuratus XP_784265 255 28831 E168 P R V H L E M E K G D T V F F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 95.2 50 N.A. 78.1 78.1 N.A. N.A. 54.4 69.8 68.3 N.A. N.A. N.A. 55 49.4
Protein Similarity: 100 99.4 97.3 55.5 N.A. 87.8 89 N.A. N.A. 67.7 80.4 81.3 N.A. N.A. N.A. 71.3 61.5
P-Site Identity: 100 100 93.3 66.6 N.A. 66.6 60 N.A. N.A. 20 46.6 46.6 N.A. N.A. N.A. 46.6 0
P-Site Similarity: 100 100 93.3 80 N.A. 80 80 N.A. N.A. 46.6 80 80 N.A. N.A. N.A. 73.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 10 0 0 0 10 0 0 0 0 28 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 0 0 0 0 73 0 64 0 19 0 0 0 0 % D
% Glu: 0 0 0 0 0 10 0 10 28 46 0 0 0 0 0 % E
% Phe: 0 37 0 0 0 0 0 10 0 0 0 0 0 10 10 % F
% Gly: 0 0 0 82 0 0 0 0 0 10 0 0 10 0 0 % G
% His: 0 0 73 10 0 0 0 0 0 0 0 10 0 0 0 % H
% Ile: 0 0 0 0 73 0 0 0 0 0 0 10 0 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 10 0 10 19 0 0 0 % K
% Leu: 0 0 0 0 10 0 0 0 0 10 0 0 0 0 10 % L
% Met: 73 0 0 0 10 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 55 19 0 0 0 % N
% Pro: 10 0 0 0 0 0 0 0 0 28 0 0 55 0 0 % P
% Gln: 0 0 0 0 0 73 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 10 0 0 0 19 10 0 0 0 0 0 0 82 0 % R
% Ser: 10 0 0 0 0 0 0 0 0 0 19 19 0 0 0 % S
% Thr: 0 0 10 0 0 0 0 0 0 10 0 28 0 0 0 % T
% Val: 0 0 10 0 10 0 0 0 0 0 0 0 10 0 73 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 46 10 0 0 0 0 73 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _