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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: OPLAH All Species: 37.58
Human Site: S866 Identified Species: 75.15
UniProt: O14841 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14841 NP_060040.1 1288 137457 S866 I G G I T P G S M P P H S T M
Chimpanzee Pan troglodytes XP_528261 1212 130154 S827 N H P S A G G S H L P D L T V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539206 1379 147579 S969 I G G I T P G S M P P H S T T
Cat Felis silvestris
Mouse Mus musculus Q8K010 1288 137593 S866 I G G I T P G S M P P H S T T
Rat Rattus norvegicus P97608 1288 137702 S866 I G G I T P G S M P P H S T T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521030 1300 139318 S878 I G G I T P G S M P P H S T S
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611675 1294 139594 S869 I G G I T P G S M P P H S T S
Honey Bee Apis mellifera XP_001121487 1287 139635 S866 I G G I T P G S M P P H S T C
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794494 1307 142838 S875 I G G A S P G S M P P F S K T
Poplar Tree Populus trichocarpa XP_002305860 1269 137853 S870 I G G I T P G S M P P F S K S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FIZ7 1266 137512 S866 V G G I T P G S M P P F S K A
Baker's Yeast Sacchar. cerevisiae P28273 1286 140409 V879 G G I L P G S V P P N S K E L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.5 N.A. 69.4 N.A. 92.5 93.9 N.A. 80.2 N.A. N.A. N.A. N.A. 61.2 65 N.A. 64.1
Protein Similarity: 100 93.1 N.A. 74 N.A. 95.6 96.1 N.A. 87.2 N.A. N.A. N.A. N.A. 74.5 76.9 N.A. 76.1
P-Site Identity: 100 26.6 N.A. 93.3 N.A. 93.3 93.3 N.A. 93.3 N.A. N.A. N.A. N.A. 93.3 93.3 N.A. 66.6
P-Site Similarity: 100 33.3 N.A. 93.3 N.A. 93.3 93.3 N.A. 93.3 N.A. N.A. N.A. N.A. 93.3 93.3 N.A. 73.3
Percent
Protein Identity: 57.2 N.A. N.A. 56.8 49 N.A.
Protein Similarity: 70.9 N.A. N.A. 71.2 66 N.A.
P-Site Identity: 80 N.A. N.A. 73.3 13.3 N.A.
P-Site Similarity: 80 N.A. N.A. 80 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 9 0 0 0 0 0 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 25 0 0 0 % F
% Gly: 9 92 84 0 0 17 92 0 0 0 0 0 0 0 0 % G
% His: 0 9 0 0 0 0 0 0 9 0 0 59 0 0 0 % H
% Ile: 75 0 9 75 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 9 25 0 % K
% Leu: 0 0 0 9 0 0 0 0 0 9 0 0 9 0 9 % L
% Met: 0 0 0 0 0 0 0 0 84 0 0 0 0 0 9 % M
% Asn: 9 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % N
% Pro: 0 0 9 0 9 84 0 0 9 92 92 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 9 9 0 9 92 0 0 0 9 84 0 25 % S
% Thr: 0 0 0 0 75 0 0 0 0 0 0 0 0 67 34 % T
% Val: 9 0 0 0 0 0 0 9 0 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _