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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: OPLAH All Species: 26.67
Human Site: Y666 Identified Species: 53.33
UniProt: O14841 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14841 NP_060040.1 1288 137457 Y666 V D K M T Q C Y F E G G Y Q E
Chimpanzee Pan troglodytes XP_528261 1212 130154 D632 P E R P V V V D D V R V R G T
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539206 1379 147579 Y763 V D K M T Q C Y F E G G Y Q E
Cat Felis silvestris
Mouse Mus musculus Q8K010 1288 137593 Y666 V E K V T Q C Y F E G G Y Q E
Rat Rattus norvegicus P97608 1288 137702 Y666 V E K V T Q C Y F E G G Y Q E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521030 1300 139318 Y678 V K T V T Q C Y F E G G Y Q E
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611675 1294 139594 Y669 A E A N T R L Y F D Q G A F D
Honey Bee Apis mellifera XP_001121487 1287 139635 Y666 F E K T T M V Y F E D G Y Q E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794494 1307 142838 Y675 V E K M T K C Y F E E G L L D
Poplar Tree Populus trichocarpa XP_002305860 1269 137853 G672 G H Y K V Y F G N G W L D T P
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FIZ7 1266 137512 E668 R H Y K V Y F E G G W H D T P
Baker's Yeast Sacchar. cerevisiae P28273 1286 140409 K679 Q K A Y F D N K W V D T A V F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.5 N.A. 69.4 N.A. 92.5 93.9 N.A. 80.2 N.A. N.A. N.A. N.A. 61.2 65 N.A. 64.1
Protein Similarity: 100 93.1 N.A. 74 N.A. 95.6 96.1 N.A. 87.2 N.A. N.A. N.A. N.A. 74.5 76.9 N.A. 76.1
P-Site Identity: 100 0 N.A. 100 N.A. 86.6 86.6 N.A. 80 N.A. N.A. N.A. N.A. 26.6 60 N.A. 60
P-Site Similarity: 100 13.3 N.A. 100 N.A. 100 100 N.A. 86.6 N.A. N.A. N.A. N.A. 53.3 66.6 N.A. 80
Percent
Protein Identity: 57.2 N.A. N.A. 56.8 49 N.A.
Protein Similarity: 70.9 N.A. N.A. 71.2 66 N.A.
P-Site Identity: 0 N.A. N.A. 0 0 N.A.
P-Site Similarity: 0 N.A. N.A. 0 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 17 0 0 0 0 0 0 0 0 0 17 0 0 % A
% Cys: 0 0 0 0 0 0 50 0 0 0 0 0 0 0 0 % C
% Asp: 0 17 0 0 0 9 0 9 9 9 17 0 17 0 17 % D
% Glu: 0 50 0 0 0 0 0 9 0 59 9 0 0 0 50 % E
% Phe: 9 0 0 0 9 0 17 0 67 0 0 0 0 9 9 % F
% Gly: 9 0 0 0 0 0 0 9 9 17 42 67 0 9 0 % G
% His: 0 17 0 0 0 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 17 50 17 0 9 0 9 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 9 0 0 0 0 9 9 9 0 % L
% Met: 0 0 0 25 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 0 9 0 9 0 0 0 0 0 0 % N
% Pro: 9 0 0 9 0 0 0 0 0 0 0 0 0 0 17 % P
% Gln: 9 0 0 0 0 42 0 0 0 0 9 0 0 50 0 % Q
% Arg: 9 0 9 0 0 9 0 0 0 0 9 0 9 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 9 9 67 0 0 0 0 0 0 9 0 17 9 % T
% Val: 50 0 0 25 25 9 17 0 0 17 0 9 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 9 0 17 0 0 0 0 % W
% Tyr: 0 0 17 9 0 17 0 67 0 0 0 0 50 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _