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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BCKDK
All Species:
29.39
Human Site:
S226
Identified Species:
46.19
UniProt:
O14874
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14874
NP_001116429.1
412
46360
S226
G
I
I
C
T
R
L
S
P
K
K
I
I
E
K
Chimpanzee
Pan troglodytes
XP_001156184
412
46441
S226
G
I
I
C
T
R
L
S
P
K
K
I
I
E
K
Rhesus Macaque
Macaca mulatta
XP_001112186
412
46391
S226
G
I
I
C
T
R
L
S
P
K
K
I
I
E
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O55028
412
46569
S226
G
I
I
C
T
R
L
S
P
K
K
I
I
E
K
Rat
Rattus norvegicus
Q00972
412
46456
S226
G
I
I
C
T
R
L
S
P
K
K
I
I
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511214
371
41647
I203
T
L
T
S
R
L
G
I
R
M
L
S
T
H
H
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085012
413
47032
W226
G
I
I
C
T
R
L
W
P
K
K
I
I
E
K
Zebra Danio
Brachydanio rerio
NP_998225
419
46906
S234
G
I
I
C
R
R
L
S
P
K
K
I
I
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91622
413
46608
Y217
R
F
L
C
D
Q
Y
Y
L
T
S
P
A
L
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q02332
401
45263
Y212
R
F
L
C
D
R
Y
Y
L
T
S
P
S
M
K
Sea Urchin
Strong. purpuratus
XP_780213
418
46942
S231
G
I
I
A
T
K
M
S
L
K
K
V
I
E
K
Poplar Tree
Populus trichocarpa
XP_002314330
369
41691
N200
S
P
V
E
V
A
Q
N
A
S
D
D
A
R
A
Maize
Zea mays
NP_001105608
364
41356
Q196
L
S
P
I
Q
V
A
Q
A
A
C
E
D
A
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187300
366
41428
S198
M
E
V
A
R
N
A
S
E
D
A
R
S
I
C
Baker's Yeast
Sacchar. cerevisiae
P40530
394
45425
P216
G
I
L
H
R
D
L
P
I
A
Q
L
I
K
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98
N.A.
N.A.
95.1
95.6
N.A.
73.3
N.A.
82
75.8
N.A.
22.7
N.A.
24.5
61.2
Protein Similarity:
100
99.7
98.5
N.A.
N.A.
96.8
96.5
N.A.
78.4
N.A.
89.8
84.4
N.A.
39.7
N.A.
42.4
74.8
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
0
N.A.
93.3
93.3
N.A.
6.6
N.A.
20
66.6
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
6.6
N.A.
93.3
93.3
N.A.
26.6
N.A.
26.6
86.6
Percent
Protein Identity:
32.2
33.5
N.A.
31.8
25.7
N.A.
Protein Similarity:
51.7
53.1
N.A.
50.9
47.5
N.A.
P-Site Identity:
0
0
N.A.
6.6
26.6
N.A.
P-Site Similarity:
13.3
6.6
N.A.
13.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
14
0
7
14
0
14
14
7
0
14
7
7
% A
% Cys:
0
0
0
60
0
0
0
0
0
0
7
0
0
0
7
% C
% Asp:
0
0
0
0
14
7
0
0
0
7
7
7
7
0
0
% D
% Glu:
0
7
0
7
0
0
0
0
7
0
0
7
0
54
7
% E
% Phe:
0
14
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
60
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
14
% H
% Ile:
0
60
54
7
0
0
0
7
7
0
0
47
60
7
0
% I
% Lys:
0
0
0
0
0
7
0
0
0
54
54
0
0
7
60
% K
% Leu:
7
7
20
0
0
7
54
0
20
0
7
7
0
7
0
% L
% Met:
7
0
0
0
0
0
7
0
0
7
0
0
0
7
0
% M
% Asn:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% N
% Pro:
0
7
7
0
0
0
0
7
47
0
0
14
0
0
0
% P
% Gln:
0
0
0
0
7
7
7
7
0
0
7
0
0
0
0
% Q
% Arg:
14
0
0
0
27
54
0
0
7
0
0
7
0
7
7
% R
% Ser:
7
7
0
7
0
0
0
54
0
7
14
7
14
0
0
% S
% Thr:
7
0
7
0
47
0
0
0
0
14
0
0
7
0
0
% T
% Val:
0
0
14
0
7
7
0
0
0
0
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
14
14
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _