Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BCKDK All Species: 28.48
Human Site: S67 Identified Species: 44.76
UniProt: O14874 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14874 NP_001116429.1 412 46360 S67 D A A A E K P S V R L T P T M
Chimpanzee Pan troglodytes XP_001156184 412 46441 S67 D A A A E K P S V R L T P T M
Rhesus Macaque Macaca mulatta XP_001112186 412 46391 S67 D A A A E K P S V R L T P T M
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O55028 412 46569 S67 D V A A E K P S V R L T P T M
Rat Rattus norvegicus Q00972 412 46456 S67 D V V A E K P S V R L T P T M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511214 371 41647 A61 T S F Y N Q S A I D V A A E K
Chicken Gallus gallus
Frog Xenopus laevis NP_001085012 413 47032 S67 D I S A E K A S V R L T P T T
Zebra Danio Brachydanio rerio NP_998225 419 46906 S75 D A S A E K P S V R L T P A T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91622 413 46608 I69 L A N I M K E I A L L P D N L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q02332 401 45263 N61 E L L V R L A N I M Q E F T L
Sea Urchin Strong. purpuratus XP_780213 418 46942 S72 D V A A K K P S V R L T P A T
Poplar Tree Populus trichocarpa XP_002314330 369 41691 P58 Q F L H K E L P I R I A R R A
Maize Zea mays NP_001105608 364 41356 P54 Q F L H K E L P I R F A R R A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_187300 366 41428 E56 S A Q F L H K E L P I R V A R
Baker's Yeast Sacchar. cerevisiae P40530 394 45425 L62 P L N Y E Y F L Q Y R P P L T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 98 N.A. N.A. 95.1 95.6 N.A. 73.3 N.A. 82 75.8 N.A. 22.7 N.A. 24.5 61.2
Protein Similarity: 100 99.7 98.5 N.A. N.A. 96.8 96.5 N.A. 78.4 N.A. 89.8 84.4 N.A. 39.7 N.A. 42.4 74.8
P-Site Identity: 100 100 100 N.A. N.A. 93.3 86.6 N.A. 0 N.A. 73.3 80 N.A. 20 N.A. 6.6 73.3
P-Site Similarity: 100 100 100 N.A. N.A. 93.3 86.6 N.A. 33.3 N.A. 80 86.6 N.A. 26.6 N.A. 33.3 80
Percent
Protein Identity: 32.2 33.5 N.A. 31.8 25.7 N.A.
Protein Similarity: 51.7 53.1 N.A. 50.9 47.5 N.A.
P-Site Identity: 6.6 6.6 N.A. 6.6 13.3 N.A.
P-Site Similarity: 33.3 26.6 N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 40 34 54 0 0 14 7 7 0 0 20 7 20 14 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 54 0 0 0 0 0 0 0 0 7 0 0 7 0 0 % D
% Glu: 7 0 0 0 54 14 7 7 0 0 0 7 0 7 0 % E
% Phe: 0 14 7 7 0 0 7 0 0 0 7 0 7 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 14 0 7 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 7 0 0 0 7 27 0 14 0 0 0 0 % I
% Lys: 0 0 0 0 20 60 7 0 0 0 0 0 0 0 7 % K
% Leu: 7 14 20 0 7 7 14 7 7 7 60 0 0 7 14 % L
% Met: 0 0 0 0 7 0 0 0 0 7 0 0 0 0 34 % M
% Asn: 0 0 14 0 7 0 0 7 0 0 0 0 0 7 0 % N
% Pro: 7 0 0 0 0 0 47 14 0 7 0 14 60 0 0 % P
% Gln: 14 0 7 0 0 7 0 0 7 0 7 0 0 0 0 % Q
% Arg: 0 0 0 0 7 0 0 0 0 67 7 7 14 14 7 % R
% Ser: 7 7 14 0 0 0 7 54 0 0 0 0 0 0 0 % S
% Thr: 7 0 0 0 0 0 0 0 0 0 0 54 0 47 27 % T
% Val: 0 20 7 7 0 0 0 0 54 0 7 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 14 0 7 0 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _