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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BCKDK
All Species:
31.52
Human Site:
T291
Identified Species:
49.52
UniProt:
O14874
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14874
NP_001116429.1
412
46360
T291
T
M
E
S
H
L
D
T
P
Y
N
V
P
D
V
Chimpanzee
Pan troglodytes
XP_001156184
412
46441
T291
T
M
E
S
H
L
D
T
P
Y
N
V
P
D
V
Rhesus Macaque
Macaca mulatta
XP_001112186
412
46391
T291
T
M
E
S
H
L
D
T
P
Y
N
V
P
D
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O55028
412
46569
T291
T
M
E
S
H
L
D
T
P
Y
N
V
P
D
V
Rat
Rattus norvegicus
Q00972
412
46456
T291
T
M
E
S
H
L
D
T
P
Y
N
V
P
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511214
371
41647
G253
R
L
C
E
H
K
Y
G
N
A
P
R
V
R
I
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085012
413
47032
T291
T
M
E
S
H
I
D
T
P
Y
N
V
P
D
I
Zebra Danio
Brachydanio rerio
NP_998225
419
46906
T299
T
M
E
S
H
L
D
T
P
Y
N
V
P
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91622
413
46608
D269
V
V
E
H
H
G
H
D
N
N
D
T
L
P
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q02332
401
45263
D263
T
V
E
Y
H
G
V
D
D
D
L
P
D
I
K
Sea Urchin
Strong. purpuratus
XP_780213
418
46942
T296
T
I
E
S
H
L
D
T
P
M
N
L
P
D
V
Poplar Tree
Populus trichocarpa
XP_002314330
369
41691
A250
L
V
K
N
S
L
R
A
V
Q
E
R
H
M
D
Maize
Zea mays
NP_001105608
364
41356
R246
E
L
V
K
N
S
L
R
A
V
Q
E
R
Y
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187300
366
41428
Q248
K
N
S
L
R
A
V
Q
E
R
F
V
D
S
D
Baker's Yeast
Sacchar. cerevisiae
P40530
394
45425
K270
Y
I
M
T
E
V
F
K
N
A
F
E
A
Q
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98
N.A.
N.A.
95.1
95.6
N.A.
73.3
N.A.
82
75.8
N.A.
22.7
N.A.
24.5
61.2
Protein Similarity:
100
99.7
98.5
N.A.
N.A.
96.8
96.5
N.A.
78.4
N.A.
89.8
84.4
N.A.
39.7
N.A.
42.4
74.8
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
6.6
N.A.
86.6
100
N.A.
13.3
N.A.
20
80
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
20
N.A.
100
100
N.A.
26.6
N.A.
26.6
93.3
Percent
Protein Identity:
32.2
33.5
N.A.
31.8
25.7
N.A.
Protein Similarity:
51.7
53.1
N.A.
50.9
47.5
N.A.
P-Site Identity:
6.6
0
N.A.
6.6
0
N.A.
P-Site Similarity:
26.6
20
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
7
7
14
0
0
7
0
0
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
54
14
7
7
7
0
14
54
14
% D
% Glu:
7
0
67
7
7
0
0
0
7
0
7
14
0
0
0
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
14
0
0
0
0
% F
% Gly:
0
0
0
0
0
14
0
7
0
0
0
0
0
0
0
% G
% His:
0
0
0
7
74
0
7
0
0
0
0
0
7
0
0
% H
% Ile:
0
14
0
0
0
7
0
0
0
0
0
0
0
7
20
% I
% Lys:
7
0
7
7
0
7
0
7
0
0
0
0
0
0
7
% K
% Leu:
7
14
0
7
0
54
7
0
0
0
7
7
7
0
0
% L
% Met:
0
47
7
0
0
0
0
0
0
7
0
0
0
7
7
% M
% Asn:
0
7
0
7
7
0
0
0
20
7
54
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
54
0
7
7
54
7
7
% P
% Gln:
0
0
0
0
0
0
0
7
0
7
7
0
0
7
0
% Q
% Arg:
7
0
0
0
7
0
7
7
0
7
0
14
7
7
0
% R
% Ser:
0
0
7
54
7
7
0
0
0
0
0
0
0
7
0
% S
% Thr:
60
0
0
7
0
0
0
54
0
0
0
7
0
0
0
% T
% Val:
7
20
7
0
0
7
14
0
7
7
0
54
7
0
47
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
7
0
0
7
0
0
47
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _