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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BCKDK
All Species:
24.24
Human Site:
Y331
Identified Species:
38.1
UniProt:
O14874
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14874
NP_001116429.1
412
46360
Y331
D
L
D
R
V
M
D
Y
H
F
T
T
A
E
A
Chimpanzee
Pan troglodytes
XP_001156184
412
46441
Y331
D
L
D
R
V
M
D
Y
H
F
T
T
A
E
A
Rhesus Macaque
Macaca mulatta
XP_001112186
412
46391
Y331
D
L
D
R
V
M
D
Y
H
F
T
T
A
E
A
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O55028
412
46569
Y331
D
L
D
R
V
M
D
Y
H
F
T
T
A
E
A
Rat
Rattus norvegicus
Q00972
412
46456
Y331
D
L
D
R
V
M
D
Y
H
F
T
T
A
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511214
371
41647
M291
K
N
A
M
R
A
T
M
E
S
H
L
D
T
P
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085012
413
47032
H332
L
E
R
V
M
D
Y
H
F
T
T
A
E
T
S
Zebra Danio
Brachydanio rerio
NP_998225
419
46906
H338
S
I
L
D
K
V
M
H
Y
H
F
S
T
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91622
413
46608
Y310
Q
T
D
Q
L
F
K
Y
M
Y
S
T
A
P
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q02332
401
45263
Y302
I
L
E
R
L
Y
N
Y
M
Y
S
T
A
P
P
Sea Urchin
Strong. purpuratus
XP_780213
418
46942
H337
L
K
K
V
F
Q
Y
H
F
T
T
A
N
D
D
Poplar Tree
Populus trichocarpa
XP_002314330
369
41691
R289
D
E
G
G
G
I
A
R
S
G
L
P
K
I
F
Maize
Zea mays
NP_001105608
364
41356
I284
V
S
D
E
G
G
G
I
P
R
S
G
L
P
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187300
366
41428
S286
E
G
G
G
I
A
R
S
G
L
P
R
I
F
T
Baker's Yeast
Sacchar. cerevisiae
P40530
394
45425
V313
G
G
G
I
T
P
E
V
E
A
L
M
F
N
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98
N.A.
N.A.
95.1
95.6
N.A.
73.3
N.A.
82
75.8
N.A.
22.7
N.A.
24.5
61.2
Protein Similarity:
100
99.7
98.5
N.A.
N.A.
96.8
96.5
N.A.
78.4
N.A.
89.8
84.4
N.A.
39.7
N.A.
42.4
74.8
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
0
N.A.
6.6
0
N.A.
26.6
N.A.
33.3
6.6
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
0
N.A.
26.6
33.3
N.A.
53.3
N.A.
66.6
20
Percent
Protein Identity:
32.2
33.5
N.A.
31.8
25.7
N.A.
Protein Similarity:
51.7
53.1
N.A.
50.9
47.5
N.A.
P-Site Identity:
6.6
6.6
N.A.
0
0
N.A.
P-Site Similarity:
13.3
13.3
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
14
7
0
0
7
0
14
47
7
34
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
40
0
47
7
0
7
34
0
0
0
0
0
7
7
7
% D
% Glu:
7
14
7
7
0
0
7
0
14
0
0
0
7
34
7
% E
% Phe:
0
0
0
0
7
7
0
0
14
34
7
0
7
7
7
% F
% Gly:
7
14
20
14
14
7
7
0
7
7
0
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
20
34
7
7
0
0
0
0
% H
% Ile:
7
7
0
7
7
7
0
7
0
0
0
0
7
7
0
% I
% Lys:
7
7
7
0
7
0
7
0
0
0
0
0
7
0
0
% K
% Leu:
14
40
7
0
14
0
0
0
0
7
14
7
7
0
0
% L
% Met:
0
0
0
7
7
34
7
7
14
0
0
7
0
0
0
% M
% Asn:
0
7
0
0
0
0
7
0
0
0
0
0
7
7
0
% N
% Pro:
0
0
0
0
0
7
0
0
7
0
7
7
0
20
14
% P
% Gln:
7
0
0
7
0
7
0
0
0
0
0
0
0
0
7
% Q
% Arg:
0
0
7
40
7
0
7
7
0
7
0
7
0
0
7
% R
% Ser:
7
7
0
0
0
0
0
7
7
7
20
7
0
0
7
% S
% Thr:
0
7
0
0
7
0
7
0
0
14
47
47
7
14
7
% T
% Val:
7
0
0
14
34
7
0
7
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
14
47
7
14
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _