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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BCKDK
All Species:
30.91
Human Site:
Y77
Identified Species:
48.57
UniProt:
O14874
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14874
NP_001116429.1
412
46360
Y77
L
T
P
T
M
M
L
Y
A
G
R
S
Q
D
G
Chimpanzee
Pan troglodytes
XP_001156184
412
46441
Y77
L
T
P
T
M
M
L
Y
A
G
R
S
Q
D
G
Rhesus Macaque
Macaca mulatta
XP_001112186
412
46391
Y77
L
T
P
T
M
M
L
Y
S
G
R
S
Q
D
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O55028
412
46569
Y77
L
T
P
T
M
M
L
Y
S
G
R
S
Q
D
G
Rat
Rattus norvegicus
Q00972
412
46456
Y77
L
T
P
T
M
M
L
Y
S
G
R
S
Q
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511214
371
41647
V71
V
A
A
E
K
A
S
V
R
L
T
P
T
T
M
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085012
413
47032
Y77
L
T
P
T
T
M
L
Y
S
G
R
S
Q
D
G
Zebra Danio
Brachydanio rerio
NP_998225
419
46906
Y85
L
T
P
A
T
M
L
Y
A
G
K
S
P
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91622
413
46608
T79
L
P
D
N
L
L
H
T
R
S
V
S
E
V
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q02332
401
45263
P71
Q
E
F
T
L
L
P
P
K
L
L
Q
M
P
S
Sea Urchin
Strong. purpuratus
XP_780213
418
46942
Y82
L
T
P
A
T
L
L
Y
T
G
K
S
P
D
G
Poplar Tree
Populus trichocarpa
XP_002314330
369
41691
L68
I
A
R
R
A
I
E
L
E
T
L
P
Y
G
L
Maize
Zea mays
NP_001105608
364
41356
L64
F
A
R
R
A
L
E
L
D
S
L
P
F
G
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187300
366
41428
I66
I
R
V
A
R
R
A
I
E
L
Q
T
L
P
Y
Baker's Yeast
Sacchar. cerevisiae
P40530
394
45425
E72
R
P
P
L
T
K
K
E
E
Y
M
L
T
I
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98
N.A.
N.A.
95.1
95.6
N.A.
73.3
N.A.
82
75.8
N.A.
22.7
N.A.
24.5
61.2
Protein Similarity:
100
99.7
98.5
N.A.
N.A.
96.8
96.5
N.A.
78.4
N.A.
89.8
84.4
N.A.
39.7
N.A.
42.4
74.8
P-Site Identity:
100
100
93.3
N.A.
N.A.
93.3
93.3
N.A.
0
N.A.
86.6
73.3
N.A.
13.3
N.A.
6.6
60
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
6.6
N.A.
93.3
80
N.A.
33.3
N.A.
20
73.3
Percent
Protein Identity:
32.2
33.5
N.A.
31.8
25.7
N.A.
Protein Similarity:
51.7
53.1
N.A.
50.9
47.5
N.A.
P-Site Identity:
0
0
N.A.
0
6.6
N.A.
P-Site Similarity:
13.3
6.6
N.A.
20
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
7
20
14
7
7
0
20
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
0
0
7
0
0
0
0
54
0
% D
% Glu:
0
7
0
7
0
0
14
7
20
0
0
0
7
0
0
% E
% Phe:
7
0
7
0
0
0
0
0
0
0
0
0
7
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
54
0
0
0
14
54
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
14
0
0
0
0
7
0
7
0
0
0
0
0
7
0
% I
% Lys:
0
0
0
0
7
7
7
0
7
0
14
0
0
0
7
% K
% Leu:
60
0
0
7
14
27
54
14
0
20
20
7
7
0
14
% L
% Met:
0
0
0
0
34
47
0
0
0
0
7
0
7
0
7
% M
% Asn:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
14
60
0
0
0
7
7
0
0
0
20
14
14
0
% P
% Gln:
7
0
0
0
0
0
0
0
0
0
7
7
40
0
0
% Q
% Arg:
7
7
14
14
7
7
0
0
14
0
40
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
7
0
27
14
0
60
0
0
14
% S
% Thr:
0
54
0
47
27
0
0
7
7
7
7
7
14
7
0
% T
% Val:
7
0
7
0
0
0
0
7
0
0
7
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
7
0
0
7
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _