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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BCKDK
All Species:
31.52
Human Site:
Y93
Identified Species:
49.52
UniProt:
O14874
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14874
NP_001116429.1
412
46360
Y93
H
L
L
K
S
A
R
Y
L
Q
Q
E
L
P
V
Chimpanzee
Pan troglodytes
XP_001156184
412
46441
Y93
H
L
L
K
S
A
R
Y
L
Q
Q
E
L
P
V
Rhesus Macaque
Macaca mulatta
XP_001112186
412
46391
Y93
H
L
L
K
S
A
R
Y
L
Q
Q
E
L
P
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O55028
412
46569
Y93
H
L
L
K
S
G
R
Y
L
Q
Q
E
L
P
V
Rat
Rattus norvegicus
Q00972
412
46456
Y93
H
L
L
K
S
G
R
Y
L
Q
Q
E
L
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511214
371
41647
G87
Y
S
G
R
S
Q
D
G
S
H
L
L
K
S
A
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085012
413
47032
Y93
H
I
L
K
S
A
R
Y
L
H
K
E
L
P
V
Zebra Danio
Brachydanio rerio
NP_998225
419
46906
Y101
H
I
L
S
S
A
R
Y
L
H
K
E
L
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91622
413
46608
D95
W
Y
V
K
S
F
E
D
V
L
V
Y
E
K
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q02332
401
45263
A87
K
M
V
S
N
W
Y
A
E
S
F
E
D
L
L
Sea Urchin
Strong. purpuratus
XP_780213
418
46942
Y98
H
L
L
R
S
A
Q
Y
L
H
K
E
L
P
V
Poplar Tree
Populus trichocarpa
XP_002314330
369
41691
V84
E
K
P
A
V
L
K
V
R
D
W
Y
L
D
S
Maize
Zea mays
NP_001105608
364
41356
V80
N
K
P
A
I
L
K
V
R
D
W
Y
L
D
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187300
366
41428
L82
L
S
D
K
P
A
V
L
K
V
R
D
W
Y
L
Baker's Yeast
Sacchar. cerevisiae
P40530
394
45425
T88
I
N
L
L
L
S
L
T
C
K
R
L
N
A
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98
N.A.
N.A.
95.1
95.6
N.A.
73.3
N.A.
82
75.8
N.A.
22.7
N.A.
24.5
61.2
Protein Similarity:
100
99.7
98.5
N.A.
N.A.
96.8
96.5
N.A.
78.4
N.A.
89.8
84.4
N.A.
39.7
N.A.
42.4
74.8
P-Site Identity:
100
100
100
N.A.
N.A.
93.3
93.3
N.A.
6.6
N.A.
80
73.3
N.A.
13.3
N.A.
6.6
73.3
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
93.3
N.A.
20
N.A.
93.3
86.6
N.A.
26.6
N.A.
33.3
93.3
Percent
Protein Identity:
32.2
33.5
N.A.
31.8
25.7
N.A.
Protein Similarity:
51.7
53.1
N.A.
50.9
47.5
N.A.
P-Site Identity:
6.6
6.6
N.A.
13.3
6.6
N.A.
P-Site Similarity:
13.3
20
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
14
0
47
0
7
0
0
0
0
0
7
14
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
7
7
0
14
0
7
7
14
0
% D
% Glu:
7
0
0
0
0
0
7
0
7
0
0
60
7
0
0
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% F
% Gly:
0
0
7
0
0
14
0
7
0
0
0
0
0
0
0
% G
% His:
54
0
0
0
0
0
0
0
0
27
0
0
0
0
0
% H
% Ile:
7
14
0
0
7
0
0
0
0
0
0
0
0
0
7
% I
% Lys:
7
14
0
54
0
0
14
0
7
7
20
0
7
7
0
% K
% Leu:
7
40
60
7
7
14
7
7
54
7
7
14
67
7
14
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
7
0
0
7
0
0
0
0
0
0
0
7
0
0
% N
% Pro:
0
0
14
0
7
0
0
0
0
0
0
0
0
54
0
% P
% Gln:
0
0
0
0
0
7
7
0
0
34
34
0
0
0
0
% Q
% Arg:
0
0
0
14
0
0
47
0
14
0
14
0
0
0
0
% R
% Ser:
0
14
0
14
67
7
0
0
7
7
0
0
0
7
14
% S
% Thr:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% T
% Val:
0
0
14
0
7
0
7
14
7
7
7
0
0
0
54
% V
% Trp:
7
0
0
0
0
7
0
0
0
0
14
0
7
0
0
% W
% Tyr:
7
7
0
0
0
0
7
54
0
0
0
20
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _