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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIP1
All Species:
28.18
Human Site:
S250
Identified Species:
51.67
UniProt:
O14893
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14893
NP_001009182.1
280
31585
S250
E
V
R
L
L
V
D
S
K
D
D
E
R
V
P
Chimpanzee
Pan troglodytes
XP_001146059
257
28910
S227
E
V
R
L
L
V
D
S
K
D
D
E
R
V
P
Rhesus Macaque
Macaca mulatta
XP_001092707
269
30339
S239
E
V
R
L
L
V
D
S
K
D
D
E
R
V
P
Dog
Lupus familis
XP_852577
246
27701
D219
L
L
V
D
S
K
D
D
E
R
V
P
A
L
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQQ4
269
30422
S239
E
V
R
L
L
V
G
S
K
D
D
E
R
V
P
Rat
Rattus norvegicus
Q9QZP1
269
30422
S239
E
V
R
L
L
V
G
S
K
D
D
E
R
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513635
265
30287
S235
E
V
R
L
L
V
E
S
K
E
D
E
R
V
P
Chicken
Gallus gallus
NP_001034391
263
30188
N233
E
V
R
V
L
E
E
N
K
N
E
E
Q
V
S
Frog
Xenopus laevis
O42260
259
29506
H227
Q
I
R
A
G
V
E
H
K
E
D
D
R
V
S
Zebra Danio
Brachydanio rerio
NP_001017608
253
29014
S224
A
V
R
A
N
L
E
S
K
D
D
D
R
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649092
245
28732
E218
R
N
Q
L
K
E
D
E
V
Q
R
A
A
P
Y
Honey Bee
Apis mellifera
XP_624141
175
20520
L148
M
R
A
K
S
K
K
L
E
I
H
E
I
G
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790467
268
30020
S239
T
L
R
A
V
M
D
S
N
T
E
E
N
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.7
96
83.9
N.A.
90.7
90.3
N.A.
80.3
75.3
71.4
62.5
N.A.
25.7
25.3
N.A.
39.6
Protein Similarity:
100
91.7
96
86.7
N.A.
93.5
94.2
N.A.
87.8
86.7
82.8
76.4
N.A.
40.3
40
N.A.
58.2
P-Site Identity:
100
100
100
6.6
N.A.
93.3
93.3
N.A.
86.6
46.6
40
46.6
N.A.
13.3
6.6
N.A.
26.6
P-Site Similarity:
100
100
100
26.6
N.A.
93.3
93.3
N.A.
100
86.6
73.3
73.3
N.A.
20
13.3
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
24
0
0
0
0
0
0
0
8
16
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
47
8
0
47
62
16
0
0
0
% D
% Glu:
54
0
0
0
0
16
31
8
16
16
16
70
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
16
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
8
0
0
8
0
0
% I
% Lys:
0
0
0
8
8
16
8
0
70
0
0
0
0
0
0
% K
% Leu:
8
16
0
54
54
8
0
8
0
0
0
0
0
24
0
% L
% Met:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
0
8
8
8
0
0
8
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
47
% P
% Gln:
8
0
8
0
0
0
0
0
0
8
0
0
8
0
0
% Q
% Arg:
8
8
77
0
0
0
0
0
0
8
8
0
62
0
0
% R
% Ser:
0
0
0
0
16
0
0
62
0
0
0
0
0
0
24
% S
% Thr:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% T
% Val:
0
62
8
8
8
54
0
0
8
0
8
0
0
62
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _