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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIP1
All Species:
31.52
Human Site:
Y171
Identified Species:
57.78
UniProt:
O14893
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14893
NP_001009182.1
280
31585
Y171
N
E
S
P
G
I
D
Y
V
Q
I
G
F
P
P
Chimpanzee
Pan troglodytes
XP_001146059
257
28910
C148
E
E
G
W
K
K
F
C
L
G
E
K
L
C
A
Rhesus Macaque
Macaca mulatta
XP_001092707
269
30339
Y160
N
E
S
P
G
I
D
Y
V
Q
I
G
F
P
P
Dog
Lupus familis
XP_852577
246
27701
R141
K
K
F
C
L
G
E
R
L
C
A
E
G
A
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQQ4
269
30422
Y160
E
E
S
P
G
I
D
Y
V
Q
V
G
F
P
P
Rat
Rattus norvegicus
Q9QZP1
269
30422
Y160
D
E
S
P
G
I
D
Y
V
Q
V
G
F
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513635
265
30287
Y156
G
E
N
P
G
I
D
Y
V
Q
I
G
F
P
P
Chicken
Gallus gallus
NP_001034391
263
30188
Y154
H
E
N
L
G
I
D
Y
I
K
V
G
F
P
P
Frog
Xenopus laevis
O42260
259
29506
Y148
S
Q
H
P
G
I
D
Y
I
K
V
G
F
P
P
Zebra Danio
Brachydanio rerio
NP_001017608
253
29014
Y145
G
V
N
P
G
L
D
Y
V
K
T
G
F
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649092
245
28732
L140
C
R
N
Q
Q
P
L
L
S
T
L
L
H
L
T
Honey Bee
Apis mellifera
XP_624141
175
20520
T70
S
S
N
D
K
E
K
T
R
I
A
P
T
L
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790467
268
30020
T160
E
N
I
C
G
Q
V
T
M
T
T
P
V
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.7
96
83.9
N.A.
90.7
90.3
N.A.
80.3
75.3
71.4
62.5
N.A.
25.7
25.3
N.A.
39.6
Protein Similarity:
100
91.7
96
86.7
N.A.
93.5
94.2
N.A.
87.8
86.7
82.8
76.4
N.A.
40.3
40
N.A.
58.2
P-Site Identity:
100
6.6
100
0
N.A.
86.6
86.6
N.A.
86.6
60
60
60
N.A.
0
0
N.A.
20
P-Site Similarity:
100
13.3
100
20
N.A.
93.3
100
N.A.
93.3
93.3
93.3
80
N.A.
13.3
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
16
0
0
8
8
% A
% Cys:
8
0
0
16
0
0
0
8
0
8
0
0
0
8
0
% C
% Asp:
8
0
0
8
0
0
62
0
0
0
0
0
0
0
8
% D
% Glu:
24
54
0
0
0
8
8
0
0
0
8
8
0
0
0
% E
% Phe:
0
0
8
0
0
0
8
0
0
0
0
0
62
0
0
% F
% Gly:
16
0
8
0
70
8
0
0
0
8
0
62
8
0
0
% G
% His:
8
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
8
0
0
54
0
0
16
8
24
0
0
0
0
% I
% Lys:
8
8
0
0
16
8
8
0
0
24
0
8
0
0
0
% K
% Leu:
0
0
0
8
8
8
8
8
16
0
8
8
8
16
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
16
8
39
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
54
0
8
0
0
0
0
0
16
0
70
70
% P
% Gln:
0
8
0
8
8
8
0
0
0
39
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
8
8
0
0
0
0
0
0
% R
% Ser:
16
8
31
0
0
0
0
0
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
16
0
16
16
0
8
0
8
% T
% Val:
0
8
0
0
0
0
8
0
47
0
31
0
8
0
8
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
62
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _