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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM4SF5
All Species:
8.79
Human Site:
T40
Identified Species:
27.62
UniProt:
O14894
Number Species:
7
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14894
NP_003954.2
197
20823
T40
G
E
T
S
W
T
N
T
N
H
L
S
L
Q
V
Chimpanzee
Pan troglodytes
XP_523818
197
20737
T40
G
E
T
S
W
T
N
T
N
H
L
S
L
Q
V
Rhesus Macaque
Macaca mulatta
XP_001095974
197
20699
T40
G
Q
T
S
W
T
N
T
N
Q
L
S
L
Q
V
Dog
Lupus familis
XP_536611
197
20751
V40
G
K
T
N
W
T
N
V
S
N
L
S
L
Q
V
Cat
Felis silvestris
Mouse
Mus musculus
Q64302
202
22225
E40
G
E
T
K
Y
A
T
E
D
H
L
S
R
F
V
Rat
Rattus norvegicus
Q9EQL5
202
21466
N39
G
G
K
V
V
D
D
N
S
H
L
S
D
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507468
202
21691
E40
G
E
T
R
Y
A
S
E
D
H
L
S
R
F
V
Chicken
Gallus gallus
XP_001234023
201
21199
N39
G
G
K
V
A
E
Q
N
D
H
I
T
D
E
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
93.4
82.7
N.A.
43.5
42
N.A.
45
41.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.9
95.9
90.3
N.A.
60.4
58.4
N.A.
61.8
60.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
66.6
N.A.
46.6
33.3
N.A.
46.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
60
53.3
N.A.
66.6
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
25
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
13
13
0
38
0
0
0
25
0
0
% D
% Glu:
0
50
0
0
0
13
0
25
0
0
0
0
0
25
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
25
0
% F
% Gly:
100
25
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
75
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% I
% Lys:
0
13
25
13
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
88
0
50
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
13
0
0
50
25
38
13
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
13
0
0
0
0
13
0
0
13
0
0
0
50
0
% Q
% Arg:
0
0
0
13
0
0
0
0
0
0
0
0
25
0
0
% R
% Ser:
0
0
0
38
0
0
13
0
25
0
0
88
0
0
0
% S
% Thr:
0
0
75
0
0
50
13
38
0
0
0
13
0
0
0
% T
% Val:
0
0
0
25
13
0
0
13
0
0
0
0
0
0
100
% V
% Trp:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
25
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _