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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRF6
All Species:
22.42
Human Site:
S220
Identified Species:
54.81
UniProt:
O14896
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14896
NP_006138.1
467
53130
S220
S
P
E
L
W
I
S
S
L
P
M
T
D
L
D
Chimpanzee
Pan troglodytes
XP_001154108
489
55005
M234
D
L
L
I
S
P
H
M
L
P
L
T
D
L
E
Rhesus Macaque
Macaca mulatta
XP_001092227
484
54595
M230
D
L
L
I
S
P
H
M
L
P
L
T
D
L
E
Dog
Lupus familis
XP_537138
531
59990
S284
S
P
E
L
W
I
S
S
L
P
M
T
D
L
D
Cat
Felis silvestris
Mouse
Mus musculus
P97431
467
53088
S220
S
P
E
L
W
I
S
S
L
P
M
T
D
L
D
Rat
Rattus norvegicus
P23570
328
37046
M111
S
A
V
R
V
Y
R
M
L
P
P
L
T
K
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508806
462
52633
S215
S
P
E
L
W
I
S
S
L
P
M
T
D
L
E
Chicken
Gallus gallus
Q90871
425
49152
H200
G
Y
T
G
Y
E
Q
H
H
S
G
Y
S
Q
M
Frog
Xenopus laevis
NP_001081215
459
52348
S210
S
P
E
M
W
I
S
S
L
P
M
T
D
L
E
Zebra Danio
Brachydanio rerio
NP_956892
492
54858
S243
T
P
E
T
W
I
S
S
L
P
M
T
D
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.4
50
86
N.A.
97.8
21.4
N.A.
89.7
34
78.3
65
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
65
65.5
86.4
N.A.
99.1
40.6
N.A.
93.7
49
86.7
75.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
33.3
33.3
100
N.A.
100
20
N.A.
93.3
0
86.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
53.3
53.3
100
N.A.
100
26.6
N.A.
100
6.6
100
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
0
0
0
0
0
0
0
0
0
0
0
80
0
30
% D
% Glu:
0
0
60
0
0
10
0
0
0
0
0
0
0
0
50
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
20
10
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
20
0
60
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
20
20
40
0
0
0
0
90
0
20
10
0
80
0
% L
% Met:
0
0
0
10
0
0
0
30
0
0
60
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
60
0
0
0
20
0
0
0
90
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
60
0
0
0
20
0
60
60
0
10
0
0
10
0
0
% S
% Thr:
10
0
10
10
0
0
0
0
0
0
0
80
10
0
0
% T
% Val:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
60
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
10
10
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _