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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IKBKB
All Species:
29.39
Human Site:
S476
Identified Species:
64.67
UniProt:
O14920
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14920
NP_001547.1
756
86564
S476
K
N
S
M
A
S
M
S
Q
Q
L
K
A
K
L
Chimpanzee
Pan troglodytes
XP_528121
757
86974
S476
K
N
S
M
A
S
M
S
Q
Q
L
K
A
K
L
Rhesus Macaque
Macaca mulatta
XP_001096913
756
86591
S476
K
N
S
M
A
S
M
S
Q
Q
L
K
A
K
L
Dog
Lupus familis
XP_539954
755
86445
S476
K
N
S
M
A
S
M
S
Q
Q
L
K
A
K
L
Cat
Felis silvestris
Mouse
Mus musculus
O88351
757
86672
A476
K
N
A
M
A
S
T
A
Q
Q
L
K
A
K
L
Rat
Rattus norvegicus
Q9QY78
757
86848
A476
K
N
A
M
A
S
T
A
Q
Q
L
K
A
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509921
757
87360
S476
K
N
S
M
A
S
M
S
Q
Q
L
K
A
K
L
Chicken
Gallus gallus
Q5ZJB4
759
86125
S487
K
N
N
M
V
S
A
S
Q
Q
L
K
A
K
L
Frog
Xenopus laevis
Q6GM53
743
85134
S471
K
N
T
M
V
S
A
S
Q
Q
L
D
A
K
L
Zebra Danio
Brachydanio rerio
Q4G3H4
758
87129
S474
K
N
M
M
F
S
F
S
Q
Q
L
K
A
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEZ5
751
86354
A494
Y
V
L
T
K
E
Q
A
R
Y
E
M
L
V
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
99.7
94.9
N.A.
91.8
91.2
N.A.
88.5
49.2
50.4
51.5
N.A.
25
N.A.
N.A.
N.A.
Protein Similarity:
100
98.4
99.7
97
N.A.
95.5
95.3
N.A.
92.7
67.8
68.3
67.9
N.A.
42.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
80
80
N.A.
100
80
73.3
80
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
100
86.6
80
80
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
0
64
0
19
28
0
0
0
0
91
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
91
0
0
0
10
0
0
0
0
0
0
82
0
91
0
% K
% Leu:
0
0
10
0
0
0
0
0
0
0
91
0
10
0
91
% L
% Met:
0
0
10
91
0
0
46
0
0
0
0
10
0
0
0
% M
% Asn:
0
91
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
91
91
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
0
0
46
0
0
91
0
73
0
0
0
0
0
0
10
% S
% Thr:
0
0
10
10
0
0
19
0
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
19
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _