KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FSCN2
All Species:
26.97
Human Site:
Y421
Identified Species:
53.94
UniProt:
O14926
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14926
NP_001070650.1
492
55057
Y421
L
S
F
S
D
G
A
Y
R
I
R
G
R
D
G
Chimpanzee
Pan troglodytes
XP_518954
683
74065
Y609
L
E
F
N
D
G
A
Y
N
I
K
G
R
F
S
Rhesus Macaque
Macaca mulatta
XP_001110926
492
54927
Y421
L
S
F
S
D
G
A
Y
Q
I
R
G
R
G
G
Dog
Lupus familis
XP_540481
492
54677
Y421
L
S
F
S
D
G
A
Y
Q
I
R
G
R
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61553
493
54489
Y423
L
E
F
N
D
G
A
Y
N
I
K
D
S
T
G
Rat
Rattus norvegicus
P85845
493
54472
Y423
L
E
F
N
D
G
A
Y
N
I
K
D
S
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426754
216
24076
W155
R
G
G
H
G
G
D
W
Y
V
A
S
S
G
A
Frog
Xenopus laevis
Q91837
483
53004
Y414
L
E
F
N
D
G
A
Y
S
L
K
D
A
T
G
Zebra Danio
Brachydanio rerio
NP_957064
490
54272
Y419
L
Q
F
S
D
G
A
Y
H
I
K
G
A
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24524
512
57261
L440
V
E
R
A
Q
K
G
L
V
H
L
K
A
H
S
Honey Bee
Apis mellifera
XP_396175
521
58237
I449
V
E
R
C
D
R
G
I
V
R
F
K
G
Q
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Q05634
496
54926
Y425
V
T
Y
K
E
G
G
Y
T
I
Q
D
S
C
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.7
97.7
90.8
N.A.
55.1
54.9
N.A.
N.A.
31.2
50.8
63.4
N.A.
36.7
40.1
N.A.
34.8
Protein Similarity:
100
54.4
98.9
95.1
N.A.
73.2
72.8
N.A.
N.A.
37.2
69.5
78.6
N.A.
55.8
56.4
N.A.
54.6
P-Site Identity:
100
60
86.6
86.6
N.A.
53.3
53.3
N.A.
N.A.
6.6
46.6
66.6
N.A.
0
6.6
N.A.
26.6
P-Site Similarity:
100
73.3
93.3
93.3
N.A.
66.6
66.6
N.A.
N.A.
20
66.6
73.3
N.A.
13.3
13.3
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
67
0
0
0
9
0
25
0
9
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
0
0
75
0
9
0
0
0
0
34
0
9
0
% D
% Glu:
0
50
0
0
9
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
67
0
0
0
0
0
0
0
9
0
0
9
0
% F
% Gly:
0
9
9
0
9
84
25
0
0
0
0
42
9
34
67
% G
% His:
0
0
0
9
0
0
0
0
9
9
0
0
0
9
0
% H
% Ile:
0
0
0
0
0
0
0
9
0
67
0
0
0
0
0
% I
% Lys:
0
0
0
9
0
9
0
0
0
0
42
17
0
0
0
% K
% Leu:
67
0
0
0
0
0
0
9
0
9
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
34
0
0
0
0
25
0
0
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
9
0
0
0
17
0
9
0
0
9
0
% Q
% Arg:
9
0
17
0
0
9
0
0
9
9
25
0
34
0
0
% R
% Ser:
0
25
0
34
0
0
0
0
9
0
0
9
34
0
17
% S
% Thr:
0
9
0
0
0
0
0
0
9
0
0
0
0
25
0
% T
% Val:
25
0
0
0
0
0
0
0
17
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
75
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _