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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HAT1 All Species: 18.79
Human Site: S150 Identified Species: 27.56
UniProt: O14929 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14929 NP_003633.1 419 49513 S150 L H T Y S V L S P T G G E N F
Chimpanzee Pan troglodytes XP_001146318 413 48959 S144 L H T Y S V L S P T G G E N F
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850080 419 49303 S150 L H T Y S V L S P T G G E N F
Cat Felis silvestris
Mouse Mus musculus Q8BY71 416 49260 S147 L H T Y T V P S Q T G G E T F
Rat Rattus norvegicus Q5M939 419 49223 S150 L H T Y S V P S P T G G E N F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514522 705 78569 N436 L H T Y S V L N K E A G E N I
Chicken Gallus gallus NP_989538 408 47950 N139 L H T Y S V H N E E A G E D I
Frog Xenopus laevis NP_001087873 402 47208 N133 V H T Y T V H N E D A G E D I
Zebra Danio Brachydanio rerio NP_001004572 408 47832 N139 Q H T Y K V H N V E A G E D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649587 405 47928 S137 I S E Y R R V S D D G S E R L
Honey Bee Apis mellifera XP_625126 408 48286 V136 E L L H S F S V N D G C T R K
Nematode Worm Caenorhab. elegans NP_499296 541 63565 E267 G E M V H K F E L K G K S Y E
Sea Urchin Strong. purpuratus XP_785091 415 48649 D145 L H S Y S N T D E A H G A T R
Poplar Tree Populus trichocarpa
Maize Zea mays Q8LPU4 468 52703 H151 T N G S A I K H D G S Y E S D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FJT8 467 52720 K158 G A T D G S S K N A E V V P S
Baker's Yeast Sacchar. cerevisiae Q12341 374 43854 L129 E K V S E Y S L N G E E F V V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 N.A. 98.5 N.A. 93.3 96.6 N.A. 45.1 80.9 71.5 68.5 N.A. 39.6 47.2 25.3 45.3
Protein Similarity: 100 98.5 N.A. 99 N.A. 96.6 97.8 N.A. 51 89.7 86.6 84.2 N.A. 60.6 67.5 43 65.6
P-Site Identity: 100 100 N.A. 100 N.A. 73.3 93.3 N.A. 66.6 53.3 40 40 N.A. 26.6 13.3 6.6 33.3
P-Site Similarity: 100 100 N.A. 100 N.A. 80 93.3 N.A. 73.3 66.6 66.6 53.3 N.A. 40 20 6.6 40
Percent
Protein Identity: N.A. 23.5 N.A. 23.1 24.8 N.A.
Protein Similarity: N.A. 44.2 N.A. 44.7 46.7 N.A.
P-Site Identity: N.A. 6.6 N.A. 6.6 0 N.A.
P-Site Similarity: N.A. 33.3 N.A. 6.6 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 7 0 0 0 0 13 25 0 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % C
% Asp: 0 0 0 7 0 0 0 7 13 19 0 0 0 19 7 % D
% Glu: 13 7 7 0 7 0 0 7 19 19 13 7 69 0 7 % E
% Phe: 0 0 0 0 0 7 7 0 0 0 0 0 7 0 32 % F
% Gly: 13 0 7 0 7 0 0 0 0 13 50 63 0 0 0 % G
% His: 0 63 0 7 7 0 19 7 0 0 7 0 0 0 0 % H
% Ile: 7 0 0 0 0 7 0 0 0 0 0 0 0 0 19 % I
% Lys: 0 7 0 0 7 7 7 7 7 7 0 7 0 0 7 % K
% Leu: 50 7 7 0 0 0 25 7 7 0 0 0 0 0 13 % L
% Met: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 0 0 7 0 25 19 0 0 0 0 32 0 % N
% Pro: 0 0 0 0 0 0 13 0 25 0 0 0 0 7 0 % P
% Gln: 7 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 7 7 0 0 0 0 0 0 0 13 7 % R
% Ser: 0 7 7 13 50 7 19 38 0 0 7 7 7 7 7 % S
% Thr: 7 0 63 0 13 0 7 0 0 32 0 0 7 13 0 % T
% Val: 7 0 7 7 0 57 7 7 7 0 0 7 7 7 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 69 0 7 0 0 0 0 0 7 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _