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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HAT1 All Species: 51.82
Human Site: S239 Identified Species: 76
UniProt: O14929 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14929 NP_003633.1 419 49513 S239 D K T R P R V S Q M L I L T P
Chimpanzee Pan troglodytes XP_001146318 413 48959 S233 D K T R P R V S Q M L I L T P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850080 419 49303 S239 D K T R P R V S Q M L I L T P
Cat Felis silvestris
Mouse Mus musculus Q8BY71 416 49260 S236 D K T R P R V S Q M L I L T P
Rat Rattus norvegicus Q5M939 419 49223 S239 D K T R P R V S Q M L I L T P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514522 705 78569 S525 D K T R P R V S Q M L I L P P
Chicken Gallus gallus NP_989538 408 47950 S228 D K T R P R V S Q M L I L P P
Frog Xenopus laevis NP_001087873 402 47208 S222 D K T R P R V S Q M L V L P P
Zebra Danio Brachydanio rerio NP_001004572 408 47832 S228 D K T R P R V S Q M L I L P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649587 405 47928 S226 Q N K R P R I S Q M L I L P P
Honey Bee Apis mellifera XP_625126 408 48286 A225 H H T R P R I A Q V L I L P P
Nematode Worm Caenorhab. elegans NP_499296 541 63565 A356 D R I R P R I A Q M L L L P Q
Sea Urchin Strong. purpuratus XP_785091 415 48649 S234 D K I R P R I S Q V L I L P P
Poplar Tree Populus trichocarpa
Maize Zea mays Q8LPU4 468 52703 S240 E S I R L R I S Q I L V L P P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FJT8 467 52720 S247 D R L R M R L S Q I L V L P S
Baker's Yeast Sacchar. cerevisiae Q12341 374 43854 S218 K K F R A K I S Q F L I F P P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 N.A. 98.5 N.A. 93.3 96.6 N.A. 45.1 80.9 71.5 68.5 N.A. 39.6 47.2 25.3 45.3
Protein Similarity: 100 98.5 N.A. 99 N.A. 96.6 97.8 N.A. 51 89.7 86.6 84.2 N.A. 60.6 67.5 43 65.6
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 93.3 93.3 86.6 93.3 N.A. 66.6 60 53.3 73.3
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 93.3 93.3 93.3 93.3 N.A. 73.3 80 80 86.6
Percent
Protein Identity: N.A. 23.5 N.A. 23.1 24.8 N.A.
Protein Similarity: N.A. 44.2 N.A. 44.7 46.7 N.A.
P-Site Identity: N.A. 46.6 N.A. 46.6 46.6 N.A.
P-Site Similarity: N.A. 73.3 N.A. 73.3 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 7 0 0 13 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 75 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 7 0 0 0 0 0 0 7 0 0 7 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 7 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 19 0 0 0 38 0 0 13 0 75 0 0 0 % I
% Lys: 7 69 7 0 0 7 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 7 0 7 0 7 0 0 0 100 7 94 0 0 % L
% Met: 0 0 0 0 7 0 0 0 0 69 0 0 0 0 0 % M
% Asn: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 82 0 0 0 0 0 0 0 0 69 88 % P
% Gln: 7 0 0 0 0 0 0 0 100 0 0 0 0 0 7 % Q
% Arg: 0 13 0 100 0 94 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 7 0 0 0 0 0 88 0 0 0 0 0 0 7 % S
% Thr: 0 0 63 0 0 0 0 0 0 0 0 0 0 32 0 % T
% Val: 0 0 0 0 0 0 57 0 0 13 0 19 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _