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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HAT1 All Species: 27.27
Human Site: S343 Identified Species: 40
UniProt: O14929 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14929 NP_003633.1 419 49513 S343 R L L V T D M S D A E Q Y R S
Chimpanzee Pan troglodytes XP_001146318 413 48959 S337 R L L V T D M S D A E Q Y R S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850080 419 49303 S343 R L L V T D M S D A E Q Y R S
Cat Felis silvestris
Mouse Mus musculus Q8BY71 416 49260 S340 R L L V T D M S D A E Q Y R S
Rat Rattus norvegicus Q5M939 419 49223 S343 R L L V T D M S D A E Q C R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514522 705 78569 G629 R L R V T D M G D A D Q S K G
Chicken Gallus gallus NP_989538 408 47950 G332 R L R A T D M G D A E Q S R S
Frog Xenopus laevis NP_001087873 402 47208 S326 R L R A T D M S D P E K S K A
Zebra Danio Brachydanio rerio NP_001004572 408 47832 N332 R L R N T D M N D E K K A R E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649587 405 47928 K330 R L F Y T N V K D E K E Y R P
Honey Bee Apis mellifera XP_625126 408 48286 T329 R L R T T D L T N E Q E Y R E
Nematode Worm Caenorhab. elegans NP_499296 541 63565 K460 R Y R A T N K K D K E E L K A
Sea Urchin Strong. purpuratus XP_785091 415 48649 S338 R L K S T D Y S N T E H A K A
Poplar Tree Populus trichocarpa
Maize Zea mays Q8LPU4 468 52703 Q361 V F L S L D S Q D H K S M D N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FJT8 467 52720 V383 T S V I T N H V R T D I L G K
Baker's Yeast Sacchar. cerevisiae Q12341 374 43854 E303 S R K S L K L E E R Q F N R L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 N.A. 98.5 N.A. 93.3 96.6 N.A. 45.1 80.9 71.5 68.5 N.A. 39.6 47.2 25.3 45.3
Protein Similarity: 100 98.5 N.A. 99 N.A. 96.6 97.8 N.A. 51 89.7 86.6 84.2 N.A. 60.6 67.5 43 65.6
P-Site Identity: 100 100 N.A. 100 N.A. 100 93.3 N.A. 60 73.3 53.3 46.6 N.A. 40 40 26.6 40
P-Site Similarity: 100 100 N.A. 100 N.A. 100 93.3 N.A. 73.3 73.3 73.3 66.6 N.A. 66.6 73.3 53.3 60
Percent
Protein Identity: N.A. 23.5 N.A. 23.1 24.8 N.A.
Protein Similarity: N.A. 44.2 N.A. 44.7 46.7 N.A.
P-Site Identity: N.A. 20 N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. 33.3 N.A. 33.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 19 0 0 0 0 0 44 0 0 13 0 19 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % C
% Asp: 0 0 0 0 0 75 0 0 75 0 13 0 0 7 0 % D
% Glu: 0 0 0 0 0 0 0 7 7 19 57 19 0 0 13 % E
% Phe: 0 7 7 0 0 0 0 0 0 0 0 7 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 13 0 0 0 0 0 7 7 % G
% His: 0 0 0 0 0 0 7 0 0 7 0 7 0 0 0 % H
% Ile: 0 0 0 7 0 0 0 0 0 0 0 7 0 0 0 % I
% Lys: 0 0 13 0 0 7 7 13 0 7 19 13 0 25 7 % K
% Leu: 0 75 38 0 13 0 13 0 0 0 0 0 13 0 7 % L
% Met: 0 0 0 0 0 0 57 0 0 0 0 0 7 0 0 % M
% Asn: 0 0 0 7 0 19 0 7 13 0 0 0 7 0 7 % N
% Pro: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 7 % P
% Gln: 0 0 0 0 0 0 0 7 0 0 13 44 0 0 0 % Q
% Arg: 82 7 38 0 0 0 0 0 7 7 0 0 0 63 0 % R
% Ser: 7 7 0 19 0 0 7 44 0 0 0 7 19 0 38 % S
% Thr: 7 0 0 7 88 0 0 7 0 13 0 0 0 0 0 % T
% Val: 7 0 7 38 0 0 7 7 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 7 0 0 7 0 0 0 0 0 38 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _