Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HAT1 All Species: 40
Human Site: T259 Identified Species: 58.67
UniProt: O14929 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14929 NP_003633.1 419 49513 T259 H G A Q L L E T V H R Y Y T E
Chimpanzee Pan troglodytes XP_001146318 413 48959 T253 H G A Q L L E T V H R Y Y T E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850080 419 49303 T259 H G A Q L L E T V H R Y Y I A
Cat Felis silvestris
Mouse Mus musculus Q8BY71 416 49260 T256 H G A Q L L E T V H R Y Y I S
Rat Rattus norvegicus Q5M939 419 49223 T259 H G A Q L L E T V H R Y Y I A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514522 705 78569 T545 H G A Q L F E T V H R Y Y I S
Chicken Gallus gallus NP_989538 408 47950 T248 H G A Q L L E T V H R Y Y M S
Frog Xenopus laevis NP_001087873 402 47208 T242 H G A Q L M E T V H R Y Y V S
Zebra Danio Brachydanio rerio NP_001004572 408 47832 T248 H G A Q L L E T V H R Y Y C T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649587 405 47928 S246 L A T Q L V E S I Y R F Y Q S
Honey Bee Apis mellifera XP_625126 408 48286 A245 L G T H L L H A I Y R E Y I G
Nematode Worm Caenorhab. elegans NP_499296 541 63565 S376 I G A S F M E S F L R D L R A
Sea Urchin Strong. purpuratus XP_785091 415 48649 T254 H G A Q F L E T M Y A D F R K
Poplar Tree Populus trichocarpa
Maize Zea mays Q8LPU4 468 52703 A260 H G L G L L E A I N Y I A Q S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FJT8 467 52720 V267 L G S Y L M E V V N N V A I T
Baker's Yeast Sacchar. cerevisiae Q12341 374 43854 A238 H G S C L Y E A I I Q S W L E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 N.A. 98.5 N.A. 93.3 96.6 N.A. 45.1 80.9 71.5 68.5 N.A. 39.6 47.2 25.3 45.3
Protein Similarity: 100 98.5 N.A. 99 N.A. 96.6 97.8 N.A. 51 89.7 86.6 84.2 N.A. 60.6 67.5 43 65.6
P-Site Identity: 100 100 N.A. 86.6 N.A. 86.6 86.6 N.A. 80 86.6 80 86.6 N.A. 33.3 33.3 26.6 46.6
P-Site Similarity: 100 100 N.A. 86.6 N.A. 86.6 86.6 N.A. 80 86.6 86.6 86.6 N.A. 66.6 46.6 40 73.3
Percent
Protein Identity: N.A. 23.5 N.A. 23.1 24.8 N.A.
Protein Similarity: N.A. 44.2 N.A. 44.7 46.7 N.A.
P-Site Identity: N.A. 33.3 N.A. 26.6 33.3 N.A.
P-Site Similarity: N.A. 46.6 N.A. 46.6 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 69 0 0 0 0 19 0 0 7 0 13 0 19 % A
% Cys: 0 0 0 7 0 0 0 0 0 0 0 0 0 7 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 13 0 0 0 % D
% Glu: 0 0 0 0 0 0 94 0 0 0 0 7 0 0 19 % E
% Phe: 0 0 0 0 13 7 0 0 7 0 0 7 7 0 0 % F
% Gly: 0 94 0 7 0 0 0 0 0 0 0 0 0 0 7 % G
% His: 75 0 0 7 0 0 7 0 0 57 0 0 0 0 0 % H
% Ile: 7 0 0 0 0 0 0 0 25 7 0 7 0 38 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % K
% Leu: 19 0 7 0 88 63 0 0 0 7 0 0 7 7 0 % L
% Met: 0 0 0 0 0 19 0 0 7 0 0 0 0 7 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 13 7 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 69 0 0 0 0 0 0 7 0 0 13 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 75 0 0 13 0 % R
% Ser: 0 0 13 7 0 0 0 13 0 0 0 7 0 0 38 % S
% Thr: 0 0 13 0 0 0 0 63 0 0 0 0 0 13 13 % T
% Val: 0 0 0 0 0 7 0 7 63 0 0 7 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % W
% Tyr: 0 0 0 7 0 7 0 0 0 19 7 57 69 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _