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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HAT1 All Species: 46.97
Human Site: Y332 Identified Species: 68.89
UniProt: O14929 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14929 NP_003633.1 419 49513 Y332 K Q H A R R V Y E I L R L L V
Chimpanzee Pan troglodytes XP_001146318 413 48959 Y326 K Q H A R R V Y E I L R L L V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850080 419 49303 Y332 K Q H A R R V Y E I L R L L V
Cat Felis silvestris
Mouse Mus musculus Q8BY71 416 49260 Y329 K Q H A R R V Y E I L R L L V
Rat Rattus norvegicus Q5M939 419 49223 Y332 K Q H A R R V Y E I L R L L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514522 705 78569 Y618 K Q H A R R V Y E I L R L R V
Chicken Gallus gallus NP_989538 408 47950 Y321 K Q H T R R V Y E I L R L R A
Frog Xenopus laevis NP_001087873 402 47208 Y315 K K H A R R V Y E I L R L R A
Zebra Danio Brachydanio rerio NP_001004572 408 47832 Y321 K K H A R R V Y E I L R L R N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649587 405 47928 Y319 P L Q V R K V Y E L L R L F Y
Honey Bee Apis mellifera XP_625126 408 48286 Y318 K K Q A R R V Y E I L R L R T
Nematode Worm Caenorhab. elegans NP_499296 541 63565 Y449 R Q Q A R R V Y E I L R Y R A
Sea Urchin Strong. purpuratus XP_785091 415 48649 Y327 K K Q V R K I Y E I L R L K S
Poplar Tree Populus trichocarpa
Maize Zea mays Q8LPU4 468 52703 W350 K K Q F L R C W E I L V F L S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FJT8 467 52720 M372 L D P I D K Y M E D Y T S V I
Baker's Yeast Sacchar. cerevisiae Q12341 374 43854 F292 H S D L S D E F L E S S R K S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 N.A. 98.5 N.A. 93.3 96.6 N.A. 45.1 80.9 71.5 68.5 N.A. 39.6 47.2 25.3 45.3
Protein Similarity: 100 98.5 N.A. 99 N.A. 96.6 97.8 N.A. 51 89.7 86.6 84.2 N.A. 60.6 67.5 43 65.6
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 93.3 80 80 80 N.A. 46.6 73.3 66.6 53.3
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 93.3 80 86.6 86.6 N.A. 60 80 73.3 73.3
Percent
Protein Identity: N.A. 23.5 N.A. 23.1 24.8 N.A.
Protein Similarity: N.A. 44.2 N.A. 44.7 46.7 N.A.
P-Site Identity: N.A. 40 N.A. 6.6 0 N.A.
P-Site Similarity: N.A. 53.3 N.A. 26.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 63 0 0 0 0 0 0 0 0 0 0 19 % A
% Cys: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 7 0 7 7 0 0 0 7 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 7 0 94 7 0 0 0 0 0 % E
% Phe: 0 0 0 7 0 0 0 7 0 0 0 0 7 7 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 7 0 57 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 0 0 7 0 0 82 0 0 0 0 7 % I
% Lys: 75 32 0 0 0 19 0 0 0 0 0 0 0 13 0 % K
% Leu: 7 7 0 7 7 0 0 0 7 7 88 0 75 38 0 % L
% Met: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % N
% Pro: 7 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 50 32 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 7 0 0 0 82 75 0 0 0 0 0 82 7 38 0 % R
% Ser: 0 7 0 0 7 0 0 0 0 0 7 7 7 0 19 % S
% Thr: 0 0 0 7 0 0 0 0 0 0 0 7 0 0 7 % T
% Val: 0 0 0 13 0 0 75 0 0 0 0 7 0 7 38 % V
% Trp: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 82 0 0 7 0 7 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _