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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HAT1 All Species: 40.91
Human Site: Y363 Identified Species: 60
UniProt: O14929 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14929 NP_003633.1 419 49513 Y363 K R R L I S P Y K K K Q R D L
Chimpanzee Pan troglodytes XP_001146318 413 48959 Y357 K R R L I S P Y K K K Q R D L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850080 419 49303 Y363 K R R L I S P Y K K K Q R D L
Cat Felis silvestris
Mouse Mus musculus Q8BY71 416 49260 Y360 K R R L I S P Y K K K Q R D L
Rat Rattus norvegicus Q5M939 419 49223 Y363 K R R L I S P Y K K K Q T D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514522 705 78569 Y649 K R R L I G P Y K K K Q R D L
Chicken Gallus gallus NP_989538 408 47950 Y352 K R R L I G P Y K K K Q R E L
Frog Xenopus laevis NP_001087873 402 47208 Y346 K K R L V G P Y K K N Q R E M
Zebra Danio Brachydanio rerio NP_001004572 408 47832 Y352 K K R L F G P Y R K N Q R E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649587 405 47928 Y350 K K R L N A V Y Y K Q L K D L
Honey Bee Apis mellifera XP_625126 408 48286 Y349 K R R L N I P Y R R E Q N D L
Nematode Worm Caenorhab. elegans NP_499296 541 63565 M480 K R R L Y A P M K K S D Q D W
Sea Urchin Strong. purpuratus XP_785091 415 48649 F358 K K R L N I P F Q K Q K A D Y
Poplar Tree Populus trichocarpa
Maize Zea mays Q8LPU4 468 52703 I381 Y D R M K G E I L G S A S G T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FJT8 467 52720 P403 K K Q V V D V P S S F E P E A
Baker's Yeast Sacchar. cerevisiae Q12341 374 43854 F323 L L N N S P S F E L K V K N R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 N.A. 98.5 N.A. 93.3 96.6 N.A. 45.1 80.9 71.5 68.5 N.A. 39.6 47.2 25.3 45.3
Protein Similarity: 100 98.5 N.A. 99 N.A. 96.6 97.8 N.A. 51 89.7 86.6 84.2 N.A. 60.6 67.5 43 65.6
P-Site Identity: 100 100 N.A. 100 N.A. 100 93.3 N.A. 93.3 86.6 60 60 N.A. 46.6 60 53.3 40
P-Site Similarity: 100 100 N.A. 100 N.A. 100 93.3 N.A. 93.3 93.3 86.6 80 N.A. 73.3 80 66.6 73.3
Percent
Protein Identity: N.A. 23.5 N.A. 23.1 24.8 N.A.
Protein Similarity: N.A. 44.2 N.A. 44.7 46.7 N.A.
P-Site Identity: N.A. 6.6 N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. 13.3 N.A. 46.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 13 0 0 0 0 0 7 7 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 0 7 0 0 0 0 0 7 0 63 0 % D
% Glu: 0 0 0 0 0 0 7 0 7 0 7 7 0 25 0 % E
% Phe: 0 0 0 0 7 0 0 13 0 0 7 0 0 0 0 % F
% Gly: 0 0 0 0 0 32 0 0 0 7 0 0 0 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 44 13 0 7 0 0 0 0 0 0 0 % I
% Lys: 88 32 0 0 7 0 0 0 57 75 50 7 13 0 0 % K
% Leu: 7 7 0 82 0 0 0 0 7 7 0 7 0 0 63 % L
% Met: 0 0 0 7 0 0 0 7 0 0 0 0 0 0 7 % M
% Asn: 0 0 7 7 19 0 0 0 0 0 13 0 7 7 0 % N
% Pro: 0 0 0 0 0 7 75 7 0 0 0 0 7 0 0 % P
% Gln: 0 0 7 0 0 0 0 0 7 0 13 63 7 0 0 % Q
% Arg: 0 57 88 0 0 0 0 0 13 7 0 0 50 0 7 % R
% Ser: 0 0 0 0 7 32 7 0 7 7 13 0 7 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 7 % T
% Val: 0 0 0 7 13 0 13 0 0 0 0 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % W
% Tyr: 7 0 0 0 7 0 0 69 7 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _