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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HAT1 All Species: 19.09
Human Site: Y78 Identified Species: 28
UniProt: O14929 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14929 NP_003633.1 419 49513 Y78 G L K I L L Y Y I A G S L S T
Chimpanzee Pan troglodytes XP_001146318 413 48959 Y72 G L K I L L Y Y I A G S L S T
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850080 419 49303 Y78 G L K I L L Y Y I A G S L S T
Cat Felis silvestris
Mouse Mus musculus Q8BY71 416 49260 Y75 G L K I L L Y Y I A G S L S T
Rat Rattus norvegicus Q5M939 419 49223 Y78 G L K I L L Y Y I A G S L S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514522 705 78569 L376 Q L K L G E K L V A L N V F V
Chicken Gallus gallus NP_989538 408 47950 F76 A G N L S T L F R I E Y T S K
Frog Xenopus laevis NP_001087873 402 47208 F70 A G N L S T M F R V Q Y S S K
Zebra Danio Brachydanio rerio NP_001004572 408 47832 F76 A G N L N T L F K V K Y T A R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649587 405 47928 L72 A G P L H I Y L G V D Y G K R
Honey Bee Apis mellifera XP_625126 408 48286 T72 Y S A G C L E T Y L G M T Y S
Nematode Worm Caenorhab. elegans NP_499296 541 63565 H197 D L E V T I H H T A Q T L Y S
Sea Urchin Strong. purpuratus XP_785091 415 48649 F72 G L K V Q L Y F S A A R L T P
Poplar Tree Populus trichocarpa
Maize Zea mays Q8LPU4 468 52703 I84 N L K I N V W I S A K S F H G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FJT8 467 52720 I82 G L K I N V W I N S I S L H S
Baker's Yeast Sacchar. cerevisiae Q12341 374 43854 V69 T F K P Y V N V K Y S A K L G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 N.A. 98.5 N.A. 93.3 96.6 N.A. 45.1 80.9 71.5 68.5 N.A. 39.6 47.2 25.3 45.3
Protein Similarity: 100 98.5 N.A. 99 N.A. 96.6 97.8 N.A. 51 89.7 86.6 84.2 N.A. 60.6 67.5 43 65.6
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 20 6.6 6.6 0 N.A. 6.6 13.3 20 46.6
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 46.6 20 20 20 N.A. 20 20 66.6 66.6
Percent
Protein Identity: N.A. 23.5 N.A. 23.1 24.8 N.A.
Protein Similarity: N.A. 44.2 N.A. 44.7 46.7 N.A.
P-Site Identity: N.A. 33.3 N.A. 40 6.6 N.A.
P-Site Similarity: N.A. 46.6 N.A. 66.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 0 7 0 0 0 0 0 0 57 7 7 0 7 0 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % D
% Glu: 0 0 7 0 0 7 7 0 0 0 7 0 0 0 0 % E
% Phe: 0 7 0 0 0 0 0 25 0 0 0 0 7 7 0 % F
% Gly: 44 25 0 7 7 0 0 0 7 0 38 0 7 0 13 % G
% His: 0 0 0 0 7 0 7 7 0 0 0 0 0 13 0 % H
% Ile: 0 0 0 44 0 13 0 13 32 7 7 0 0 0 0 % I
% Lys: 0 0 63 0 0 0 7 0 13 0 13 0 7 7 13 % K
% Leu: 0 63 0 32 32 44 13 13 0 7 7 0 50 7 0 % L
% Met: 0 0 0 0 0 0 7 0 0 0 0 7 0 0 0 % M
% Asn: 7 0 19 0 19 0 7 0 7 0 0 7 0 0 0 % N
% Pro: 0 0 7 7 0 0 0 0 0 0 0 0 0 0 7 % P
% Gln: 7 0 0 0 7 0 0 0 0 0 13 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 13 0 0 7 0 0 13 % R
% Ser: 0 7 0 0 13 0 0 0 13 7 7 44 7 44 19 % S
% Thr: 7 0 0 0 7 19 0 7 7 0 0 7 19 7 32 % T
% Val: 0 0 0 13 0 19 0 7 7 19 0 0 7 0 7 % V
% Trp: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 7 0 44 32 7 7 0 25 0 13 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _