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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE2L6
All Species:
19.39
Human Site:
Y21
Identified Species:
32.82
UniProt:
O14933
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14933
NP_004214.1
153
17769
Y21
L
Q
K
K
P
P
P
Y
L
R
N
L
S
S
D
Chimpanzee
Pan troglodytes
XP_521987
152
17619
Y20
L
Q
K
K
P
P
P
Y
L
R
N
L
S
S
D
Rhesus Macaque
Macaca mulatta
XP_001088425
154
17778
N21
I
R
K
C
G
M
K
N
F
G
N
I
Q
V
D
Dog
Lupus familis
XP_533174
153
17512
Y21
L
Q
A
K
L
P
P
Y
L
R
D
L
F
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZU9
153
17822
Y21
L
S
K
E
L
P
P
Y
L
R
Q
L
S
S
D
Rat
Rattus norvegicus
Q4V8J2
153
17788
Y21
L
S
K
E
L
P
P
Y
L
R
H
L
S
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511497
126
14562
D14
Y
V
L
Q
E
L
E
D
L
Q
N
A
P
P
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086444
154
17827
N21
I
R
K
S
G
M
K
N
F
R
N
I
Q
V
D
Zebra Danio
Brachydanio rerio
NP_001002072
154
17840
N21
I
R
K
S
G
M
K
N
F
R
N
I
Q
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52487
153
17728
T21
L
V
E
A
K
M
S
T
L
R
N
I
E
S
S
Honey Bee
Apis mellifera
XP_397261
158
18153
N21
L
R
A
S
A
M
K
N
F
T
N
I
Q
V
D
Nematode Worm
Caenorhab. elegans
P35129
147
16687
C21
G
R
D
P
P
A
Q
C
S
A
G
P
V
G
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C9Y7
149
16692
N20
M
Q
R
H
P
P
A
N
C
S
A
G
P
V
A
Baker's Yeast
Sacchar. cerevisiae
P15731
148
16437
T20
D
L
E
R
D
P
P
T
S
C
S
A
G
P
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
53.2
70.5
N.A.
76.4
73.8
N.A.
56.2
N.A.
54.5
53.2
N.A.
50.3
53.1
35.9
N.A.
Protein Similarity:
100
99.3
70.1
86.2
N.A.
86.9
86.9
N.A.
69.9
N.A.
71.4
70.1
N.A.
67.9
65.8
56.2
N.A.
P-Site Identity:
100
100
20
73.3
N.A.
73.3
73.3
N.A.
13.3
N.A.
26.6
26.6
N.A.
33.3
20
13.3
N.A.
P-Site Similarity:
100
100
40
80
N.A.
80
86.6
N.A.
26.6
N.A.
46.6
46.6
N.A.
46.6
33.3
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.9
35.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.5
53.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
8
8
8
8
0
0
8
8
15
0
0
8
% A
% Cys:
0
0
0
8
0
0
0
8
8
8
0
0
0
0
0
% C
% Asp:
8
0
8
0
8
0
0
8
0
0
8
0
0
0
72
% D
% Glu:
0
0
15
15
8
0
8
0
0
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
29
0
0
0
8
0
0
% F
% Gly:
8
0
0
0
22
0
0
0
0
8
8
8
8
8
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
22
0
0
0
0
0
0
0
0
0
0
36
0
0
0
% I
% Lys:
0
0
50
22
8
0
29
0
0
0
0
0
0
0
0
% K
% Leu:
50
8
8
0
22
8
0
0
50
0
0
36
0
0
0
% L
% Met:
8
0
0
0
0
36
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
36
0
0
58
0
0
0
0
% N
% Pro:
0
0
0
8
29
50
43
0
0
0
0
8
15
15
0
% P
% Gln:
0
29
0
8
0
0
8
0
0
8
8
0
29
0
8
% Q
% Arg:
0
36
8
8
0
0
0
0
0
58
0
0
0
0
0
% R
% Ser:
0
15
0
22
0
0
8
0
15
8
8
0
29
43
8
% S
% Thr:
0
0
0
0
0
0
0
15
0
8
0
0
0
0
0
% T
% Val:
0
15
0
0
0
0
0
0
0
0
0
0
8
36
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
36
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _