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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE2L6 All Species: 37.88
Human Site: Y46 Identified Species: 64.1
UniProt: O14933 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14933 NP_004214.1 153 17769 Y46 L L P D Q P P Y H L K A F N L
Chimpanzee Pan troglodytes XP_521987 152 17619 Y45 L L P D Q P P Y H L K A F N L
Rhesus Macaque Macaca mulatta XP_001088425 154 17778 Y46 I V P D N P P Y D K G A F R I
Dog Lupus familis XP_533174 153 17512 Y46 L L P E K P P Y N L K A F H L
Cat Felis silvestris
Mouse Mus musculus Q9QZU9 153 17822 Y46 L L P D Q L P Y G L K A F Q V
Rat Rattus norvegicus Q4V8J2 153 17788 Y46 L L P D Q L P Y R L K A F G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511497 126 14562 L35 S D D A N V L L W H G L L L P
Chicken Gallus gallus
Frog Xenopus laevis NP_001086444 154 17827 Y46 I V P D N P P Y D K G A F R I
Zebra Danio Brachydanio rerio NP_001002072 154 17840 Y46 I V P D N P P Y D K G A F R I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P52487 153 17728 Y46 L V P E K A P Y N K G A F R I
Honey Bee Apis mellifera XP_397261 158 18153 Y46 I L P D N P P Y N K G A F R I
Nematode Worm Caenorhab. elegans P35129 147 16687 Y45 M G P P E S P Y Q G G V F F L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C9Y7 149 16692 Y46 M G P H D S P Y S G G V F T V
Baker's Yeast Sacchar. cerevisiae P15731 148 16437 Y46 M G P A D S P Y A G G V F F L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 53.2 70.5 N.A. 76.4 73.8 N.A. 56.2 N.A. 54.5 53.2 N.A. 50.3 53.1 35.9 N.A.
Protein Similarity: 100 99.3 70.1 86.2 N.A. 86.9 86.9 N.A. 69.9 N.A. 71.4 70.1 N.A. 67.9 65.8 56.2 N.A.
P-Site Identity: 100 100 46.6 73.3 N.A. 73.3 80 N.A. 0 N.A. 46.6 46.6 N.A. 40 53.3 33.3 N.A.
P-Site Similarity: 100 100 66.6 100 N.A. 80 80 N.A. 0 N.A. 66.6 66.6 N.A. 73.3 73.3 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 33.9 35.9 N.A.
Protein Similarity: N.A. N.A. N.A. 53.5 53.5 N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 15 0 8 0 0 8 0 0 72 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 8 58 15 0 0 0 22 0 0 0 0 0 0 % D
% Glu: 0 0 0 15 8 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 93 15 0 % F
% Gly: 0 22 0 0 0 0 0 0 8 22 65 0 0 8 0 % G
% His: 0 0 0 8 0 0 0 0 15 8 0 0 0 8 0 % H
% Ile: 29 0 0 0 0 0 0 0 0 0 0 0 0 0 36 % I
% Lys: 0 0 0 0 15 0 0 0 0 36 36 0 0 0 0 % K
% Leu: 43 43 0 0 0 15 8 8 0 36 0 8 8 8 43 % L
% Met: 22 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 36 0 0 0 22 0 0 0 0 15 0 % N
% Pro: 0 0 93 8 0 50 93 0 0 0 0 0 0 0 8 % P
% Gln: 0 0 0 0 29 0 0 0 8 0 0 0 0 8 0 % Q
% Arg: 0 0 0 0 0 0 0 0 8 0 0 0 0 36 0 % R
% Ser: 8 0 0 0 0 22 0 0 8 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % T
% Val: 0 29 0 0 0 8 0 0 0 0 0 22 0 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 93 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _