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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE2L6
All Species:
43.33
Human Site:
Y61
Identified Species:
73.33
UniProt:
O14933
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14933
NP_004214.1
153
17769
Y61
R
I
S
F
P
P
E
Y
P
F
K
P
P
M
I
Chimpanzee
Pan troglodytes
XP_521987
152
17619
Y60
R
I
S
F
P
P
E
Y
P
F
K
P
P
M
I
Rhesus Macaque
Macaca mulatta
XP_001088425
154
17778
Y61
E
I
N
F
P
A
E
Y
P
F
K
P
P
K
I
Dog
Lupus familis
XP_533174
153
17512
Y61
R
I
S
F
P
E
D
Y
P
F
K
P
P
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZU9
153
17822
Y61
R
I
D
F
P
R
E
Y
P
F
K
P
P
T
L
Rat
Rattus norvegicus
Q4V8J2
153
17788
Y61
R
I
D
F
P
R
E
Y
P
L
K
P
P
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511497
126
14562
R50
D
T
P
P
Y
N
L
R
A
F
K
V
K
I
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086444
154
17827
Y61
E
I
N
F
P
A
E
Y
P
F
K
P
P
K
I
Zebra Danio
Brachydanio rerio
NP_001002072
154
17840
Y61
E
I
T
F
P
A
E
Y
P
F
K
P
P
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52487
153
17728
Y61
E
I
N
F
P
P
Q
Y
P
F
M
P
P
K
I
Honey Bee
Apis mellifera
XP_397261
158
18153
Y61
E
I
N
F
P
A
E
Y
P
F
K
P
P
K
I
Nematode Worm
Caenorhab. elegans
P35129
147
16687
Y60
T
I
H
F
P
T
D
Y
P
F
K
P
P
K
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C9Y7
149
16692
Y61
S
I
D
F
S
S
D
Y
P
F
K
P
P
K
V
Baker's Yeast
Sacchar. cerevisiae
P15731
148
16437
Y61
S
I
H
F
P
T
D
Y
P
F
K
P
P
K
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
53.2
70.5
N.A.
76.4
73.8
N.A.
56.2
N.A.
54.5
53.2
N.A.
50.3
53.1
35.9
N.A.
Protein Similarity:
100
99.3
70.1
86.2
N.A.
86.9
86.9
N.A.
69.9
N.A.
71.4
70.1
N.A.
67.9
65.8
56.2
N.A.
P-Site Identity:
100
100
73.3
73.3
N.A.
73.3
66.6
N.A.
13.3
N.A.
73.3
73.3
N.A.
66.6
73.3
60
N.A.
P-Site Similarity:
100
100
80
86.6
N.A.
80
73.3
N.A.
20
N.A.
80
80
N.A.
80
80
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.9
35.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.5
53.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
66.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
29
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
22
0
0
0
29
0
0
0
0
0
0
0
0
% D
% Glu:
36
0
0
0
0
8
58
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
93
0
0
0
0
0
93
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
93
0
0
0
0
0
0
0
0
0
0
0
8
58
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
93
0
8
58
0
% K
% Leu:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
15
0
% M
% Asn:
0
0
29
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
8
86
22
0
0
93
0
0
93
93
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
36
0
0
0
0
15
0
8
0
0
0
0
0
0
0
% R
% Ser:
15
0
22
0
8
8
0
0
0
0
0
0
0
0
8
% S
% Thr:
8
8
8
0
0
15
0
0
0
0
0
0
0
22
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
22
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
93
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _