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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TFEC All Species: 19.49
Human Site: T2 Identified Species: 61.27
UniProt: O14948 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14948 NP_001018068.1 347 38788 T2 _ _ _ _ _ _ M T L D H Q I I N
Chimpanzee Pan troglodytes A2T713 347 38902 T2 _ _ _ _ _ _ M T L D H Q I I N
Rhesus Macaque Macaca mulatta XP_001101140 347 38862 I2 _ _ _ _ _ _ M I L D H Q I I N
Dog Lupus familis XP_532523 347 38922 T2 _ _ _ _ _ _ M T L D Y Q I V N
Cat Felis silvestris
Mouse Mus musculus Q9WTW4 317 35125 T2 _ _ _ _ _ _ M T F D C R V C D
Rat Rattus norvegicus Q63302 317 35156 T2 _ _ _ _ _ _ M T L D H R L F S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510513 377 42409 T34 Q Q V K Q Y L T L D S K L V N
Chicken Gallus gallus Q5XFQ6 377 42496 T36 K Q Y L T L D T K L S S Q T L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 97.4 89.3 N.A. 70 72.3 N.A. 64.4 66.8 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 98.2 93.9 N.A. 76.3 78.6 N.A. 75 78.7 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 88.8 77.7 N.A. 33.3 55.5 N.A. 26.6 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 88.8 100 N.A. 66.6 88.8 N.A. 60 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 13 0 0 13 0 % C
% Asp: 0 0 0 0 0 0 13 0 0 88 0 0 0 0 13 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 13 0 0 0 0 13 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 50 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 13 0 0 0 0 50 38 0 % I
% Lys: 13 0 0 13 0 0 0 0 13 0 0 13 0 0 0 % K
% Leu: 0 0 0 13 0 13 13 0 75 13 0 0 25 0 13 % L
% Met: 0 0 0 0 0 0 75 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 63 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 13 25 0 0 13 0 0 0 0 0 0 50 13 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 25 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 25 13 0 0 13 % S
% Thr: 0 0 0 0 13 0 0 88 0 0 0 0 0 13 0 % T
% Val: 0 0 13 0 0 0 0 0 0 0 0 0 13 25 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 13 0 0 13 0 0 0 0 13 0 0 0 0 % Y
% Spaces: 75 75 75 75 75 75 0 0 0 0 0 0 0 0 0 % _