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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYL12B
All Species:
27.27
Human Site:
T117
Identified Species:
50
UniProt:
O14950
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14950
NP_001138416.1
172
19779
T117
F
D
E
E
A
T
G
T
I
Q
E
D
Y
L
R
Chimpanzee
Pan troglodytes
XP_512041
204
23514
T149
F
D
E
E
A
T
G
T
I
Q
E
D
Y
L
R
Rhesus Macaque
Macaca mulatta
XP_001084519
171
19732
T116
F
D
E
E
A
T
G
T
I
Q
E
D
Y
L
R
Dog
Lupus familis
XP_537316
172
19775
T117
F
D
E
E
A
T
G
T
I
Q
E
D
Y
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3THE2
172
19761
T117
F
D
E
E
A
T
G
T
I
Q
E
D
Y
L
R
Rat
Rattus norvegicus
P18666
172
19820
T117
F
D
E
E
A
T
G
T
I
Q
E
D
Y
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510118
172
19818
S117
F
D
E
E
A
T
G
S
I
Q
E
D
Y
L
R
Chicken
Gallus gallus
P24032
172
19893
F117
F
D
E
E
A
T
G
F
I
Q
E
D
Y
L
R
Frog
Xenopus laevis
NP_001080779
172
19827
F117
F
D
E
E
A
I
G
F
I
Q
E
D
N
L
R
Zebra Danio
Brachydanio rerio
NP_001124061
172
19791
F117
F
D
E
E
G
T
G
F
I
Q
E
D
Y
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40423
174
19936
V119
F
D
E
E
N
M
G
V
L
P
E
D
R
L
R
Honey Bee
Apis mellifera
XP_623372
174
19975
H119
F
D
E
E
N
T
G
H
I
N
E
E
R
L
R
Nematode Worm
Caenorhab. elegans
Q09510
172
19922
K117
F
D
E
D
N
S
G
K
L
N
E
E
H
L
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.3
98.2
99.4
N.A.
100
99.4
N.A.
97.6
98.2
95.3
94.7
N.A.
81.6
82.1
71.5
N.A.
Protein Similarity:
100
83.3
98.8
100
N.A.
100
99.4
N.A.
98.8
98.8
97
97.6
N.A.
89.6
89.6
88.9
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
80
86.6
N.A.
60
66.6
46.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
80
86.6
N.A.
66.6
73.3
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
70
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
100
0
8
0
0
0
0
0
0
0
85
0
0
0
% D
% Glu:
0
0
100
93
0
0
0
0
0
0
100
16
0
0
0
% E
% Phe:
100
0
0
0
0
0
0
24
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
100
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
85
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
16
0
0
0
0
100
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
24
0
0
0
0
16
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
77
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
100
% R
% Ser:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
77
0
47
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
70
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _