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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYL12B All Species: 53.64
Human Site: T129 Identified Species: 98.33
UniProt: O14950 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14950 NP_001138416.1 172 19779 T129 Y L R E L L T T M G D R F T D
Chimpanzee Pan troglodytes XP_512041 204 23514 T161 Y L R E L L T T M G D R F T D
Rhesus Macaque Macaca mulatta XP_001084519 171 19732 T128 Y L R E L L T T M G D R F T D
Dog Lupus familis XP_537316 172 19775 T129 Y L R E L L T T M G D R F T D
Cat Felis silvestris
Mouse Mus musculus Q3THE2 172 19761 T129 Y L R E L L T T M G D R F T D
Rat Rattus norvegicus P18666 172 19820 T129 Y L R E L L T T M G D R F T D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510118 172 19818 T129 Y L R E L L T T M G D R F T D
Chicken Gallus gallus P24032 172 19893 T129 Y L R E L L T T M G D R F T D
Frog Xenopus laevis NP_001080779 172 19827 T129 N L R E L L T T M G D R F T D
Zebra Danio Brachydanio rerio NP_001124061 172 19791 T129 Y L R E L L T T M G D R F T D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40423 174 19936 T131 R L R E L L T T M G D R F T D
Honey Bee Apis mellifera XP_623372 174 19975 T131 R L R E L L T T M G D R F T D
Nematode Worm Caenorhab. elegans Q09510 172 19922 T129 H L R E L L T T M G E R Y S E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.3 98.2 99.4 N.A. 100 99.4 N.A. 97.6 98.2 95.3 94.7 N.A. 81.6 82.1 71.5 N.A.
Protein Similarity: 100 83.3 98.8 100 N.A. 100 99.4 N.A. 98.8 98.8 97 97.6 N.A. 89.6 89.6 88.9 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 93.3 100 N.A. 93.3 93.3 66.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 93.3 100 N.A. 93.3 93.3 100 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 93 0 0 0 93 % D
% Glu: 0 0 0 100 0 0 0 0 0 0 8 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 93 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 100 0 0 100 100 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 16 0 100 0 0 0 0 0 0 0 0 100 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % S
% Thr: 0 0 0 0 0 0 100 100 0 0 0 0 0 93 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 70 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _