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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAB7L1
All Species:
23.33
Human Site:
S185
Identified Species:
46.67
UniProt:
O14966
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14966
NP_001129134.1
203
23155
S185
T
E
D
I
M
S
L
S
T
Q
G
D
Y
I
N
Chimpanzee
Pan troglodytes
XP_001162387
193
22028
S175
T
E
D
I
M
S
L
S
T
Q
G
D
Y
I
N
Rhesus Macaque
Macaca mulatta
XP_001091582
203
23132
S185
R
E
D
I
M
S
L
S
T
Q
G
D
Y
I
N
Dog
Lupus familis
XP_536104
203
23071
S184
S
R
E
D
M
S
L
S
T
Q
G
D
Y
I
N
Cat
Felis silvestris
Mouse
Mus musculus
Q91YQ1
204
23071
S185
R
E
D
V
M
S
L
S
T
Q
G
N
Y
I
N
Rat
Rattus norvegicus
Q63481
204
23099
S185
R
E
D
I
M
S
S
S
T
Q
G
N
Y
I
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520779
162
18481
Q145
G
L
G
S
L
P
S
Q
G
D
Y
I
N
L
Q
Chicken
Gallus gallus
Q5ZIT5
200
22530
N183
V
K
E
P
N
S
E
N
V
D
I
S
S
G
G
Frog
Xenopus laevis
NP_001085684
204
23107
S185
Q
S
G
N
S
S
F
S
T
H
G
D
Y
I
N
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P16976
208
23293
V187
L
E
R
K
P
S
N
V
V
Q
M
K
G
R
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P28188
203
22630
A174
A
S
I
K
E
R
M
A
S
Q
P
A
G
N
N
Baker's Yeast
Sacchar. cerevisiae
P01123
206
23196
K185
L
N
E
T
T
Q
K
K
E
D
K
G
N
V
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
98.5
94
N.A.
93.6
93.6
N.A.
69.4
36.4
72
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
95
98.5
97
N.A.
96.5
96
N.A.
74.8
60.5
79.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
73.3
N.A.
80
80
N.A.
0
6.6
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
93.3
86.6
N.A.
13.3
26.6
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
33.1
N.A.
32.5
34.4
N.A.
Protein Similarity:
N.A.
59.1
N.A.
57.6
57.7
N.A.
P-Site Identity:
N.A.
20
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
20
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
42
9
0
0
0
0
0
25
0
42
0
0
0
% D
% Glu:
0
50
25
0
9
0
9
0
9
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
17
0
0
0
0
0
9
0
59
9
17
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
9
34
0
0
0
0
0
0
9
9
0
59
0
% I
% Lys:
0
9
0
17
0
0
9
9
0
0
9
9
0
0
0
% K
% Leu:
17
9
0
0
9
0
42
0
0
0
0
0
0
9
0
% L
% Met:
0
0
0
0
50
0
9
0
0
0
9
0
0
0
0
% M
% Asn:
0
9
0
9
9
0
9
9
0
0
0
17
17
9
75
% N
% Pro:
0
0
0
9
9
9
0
0
0
0
9
0
0
0
9
% P
% Gln:
9
0
0
0
0
9
0
9
0
67
0
0
0
0
9
% Q
% Arg:
25
9
9
0
0
9
0
0
0
0
0
0
0
9
0
% R
% Ser:
9
17
0
9
9
75
17
59
9
0
0
9
9
0
0
% S
% Thr:
17
0
0
9
9
0
0
0
59
0
0
0
0
0
0
% T
% Val:
9
0
0
9
0
0
0
9
17
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
0
59
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _