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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DSCR3
All Species:
38.79
Human Site:
S208
Identified Species:
77.58
UniProt:
O14972
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14972
NP_006043.1
297
33010
S208
S
S
E
A
A
I
R
S
V
E
L
Q
L
V
R
Chimpanzee
Pan troglodytes
XP_531457
297
32978
S208
S
S
E
A
A
I
R
S
V
E
L
Q
L
V
R
Rhesus Macaque
Macaca mulatta
XP_001083723
297
32978
S208
S
S
E
A
A
I
R
S
V
E
L
Q
L
V
R
Dog
Lupus familis
XP_852928
529
57500
S208
S
S
E
A
A
I
K
S
I
E
L
Q
L
V
R
Cat
Felis silvestris
Mouse
Mus musculus
O35075
297
32952
S208
H
S
D
A
A
I
R
S
I
E
L
Q
L
V
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509657
354
39033
S265
N
S
E
A
A
I
K
S
I
E
L
Q
L
V
R
Chicken
Gallus gallus
XP_416728
297
33026
S208
S
A
E
A
A
V
K
S
I
E
L
Q
L
V
R
Frog
Xenopus laevis
NP_001084757
297
33277
S208
T
S
E
V
A
I
K
S
I
E
L
Q
L
V
R
Zebra Danio
Brachydanio rerio
NP_001003421
297
33329
S208
N
S
E
V
P
I
K
S
I
E
L
Q
L
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649249
295
33051
A214
D
E
G
Y
S
K
D
A
T
E
I
Q
T
I
Q
Honey Bee
Apis mellifera
XP_001122268
257
29117
C179
Q
L
V
R
V
E
T
C
G
S
A
E
G
Y
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200151
302
33273
S208
S
C
N
A
P
I
K
S
V
E
I
Q
L
V
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.3
52.1
N.A.
91.5
N.A.
N.A.
74.8
91.9
83.1
77.7
N.A.
48.1
55.2
N.A.
59.6
Protein Similarity:
100
100
99.6
55.2
N.A.
96.3
N.A.
N.A.
81.3
96.9
94.2
91.2
N.A.
69.6
71.7
N.A.
75.5
P-Site Identity:
100
100
100
86.6
N.A.
80
N.A.
N.A.
80
73.3
73.3
66.6
N.A.
13.3
0
N.A.
66.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
100
100
93.3
86.6
N.A.
46.6
6.6
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
67
67
0
0
9
0
0
9
0
0
0
0
% A
% Cys:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
67
0
0
9
0
0
0
92
0
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
9
0
0
0
9
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
75
0
0
50
0
17
0
0
9
0
% I
% Lys:
0
0
0
0
0
9
50
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
0
0
0
0
0
0
0
0
75
0
84
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
17
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
0
0
0
0
0
0
0
0
0
92
0
0
9
% Q
% Arg:
0
0
0
9
0
0
34
0
0
0
0
0
0
0
84
% R
% Ser:
50
67
0
0
9
0
0
84
0
9
0
0
0
0
9
% S
% Thr:
9
0
0
0
0
0
9
0
9
0
0
0
9
0
0
% T
% Val:
0
0
9
17
9
9
0
0
34
0
0
0
0
84
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _