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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP1R12A
All Species:
18.18
Human Site:
S680
Identified Species:
57.14
UniProt:
O14974
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14974
NP_001137357.1
1030
115281
S680
V
R
D
E
E
S
E
S
Q
R
K
A
R
S
R
Chimpanzee
Pan troglodytes
XP_001163432
1030
115419
S680
V
R
D
E
E
S
E
S
Q
R
K
A
R
S
R
Rhesus Macaque
Macaca mulatta
XP_001086127
1029
115179
S680
V
R
D
E
E
S
E
S
Q
R
K
A
R
S
R
Dog
Lupus familis
XP_852025
1029
115190
S679
V
R
D
E
E
S
E
S
Q
R
K
A
R
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBR7
1029
114978
R680
D
E
E
S
E
S
Q
R
K
A
R
S
R
Q
A
Rat
Rattus norvegicus
Q10728
1032
115264
E680
P
V
R
D
E
E
S
E
S
Q
R
K
A
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90623
1004
111588
S679
V
R
D
E
E
S
E
S
Q
R
K
A
R
S
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DRG7
1049
117303
G684
T
T
T
T
S
T
T
G
T
V
L
G
S
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.5
98.1
N.A.
93.7
94
N.A.
N.A.
84.2
N.A.
73.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
99.7
99.3
N.A.
96.6
97.1
N.A.
N.A.
91.1
N.A.
83.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
20
6.6
N.A.
N.A.
100
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
53.3
26.6
N.A.
N.A.
100
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
13
0
63
13
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
0
63
13
0
0
0
0
0
0
0
0
0
13
0
% D
% Glu:
0
13
13
63
88
13
63
13
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
13
0
0
0
13
0
0
13
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
13
0
63
13
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
13
0
63
13
0
0
0
13
0
% Q
% Arg:
0
63
13
0
0
0
0
13
0
63
25
0
75
13
63
% R
% Ser:
0
0
0
13
13
75
13
63
13
0
0
13
13
63
13
% S
% Thr:
13
13
13
13
0
13
13
0
13
0
0
0
0
0
0
% T
% Val:
63
13
0
0
0
0
0
0
0
13
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _