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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GAK
All Species:
23.33
Human Site:
T114
Identified Species:
64.17
UniProt:
O14976
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14976
NP_005246.2
1311
143191
T114
I
G
K
E
E
S
D
T
G
Q
A
E
F
L
L
Chimpanzee
Pan troglodytes
XP_001140835
1311
143128
T114
I
G
K
E
E
S
D
T
G
Q
A
E
F
L
L
Rhesus Macaque
Macaca mulatta
XP_001094120
1194
129694
S88
I
K
L
C
D
F
G
S
A
T
T
I
S
H
Y
Dog
Lupus familis
XP_536279
800
86121
Cat
Felis silvestris
Mouse
Mus musculus
Q99KY4
1305
143622
T114
I
G
K
E
E
S
D
T
G
Q
A
E
F
L
L
Rat
Rattus norvegicus
P97874
1305
143685
T114
I
G
K
E
E
S
D
T
G
Q
A
E
F
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512602
1331
147587
T114
I
G
K
E
E
S
D
T
G
Q
A
E
F
L
L
Chicken
Gallus gallus
XP_424873
1296
143627
K102
L
L
L
T
E
L
C
K
G
Q
L
V
E
F
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919224
1278
141216
T114
I
S
K
E
E
S
D
T
G
Q
A
E
F
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
88.5
47.8
N.A.
82.6
82.3
N.A.
74.2
70.1
N.A.
66.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
89.2
52.1
N.A.
88.4
88.3
N.A.
83.3
80.3
N.A.
77.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
0
N.A.
100
100
N.A.
100
26.6
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
0
N.A.
100
100
N.A.
100
33.3
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
12
0
67
0
0
0
0
% A
% Cys:
0
0
0
12
0
0
12
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
12
0
67
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
67
78
0
0
0
0
0
0
67
12
0
0
% E
% Phe:
0
0
0
0
0
12
0
0
0
0
0
0
67
12
0
% F
% Gly:
0
56
0
0
0
0
12
0
78
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% H
% Ile:
78
0
0
0
0
0
0
0
0
0
0
12
0
0
12
% I
% Lys:
0
12
67
0
0
0
0
12
0
0
0
0
0
0
0
% K
% Leu:
12
12
23
0
0
12
0
0
0
0
12
0
0
67
67
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
78
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
12
0
0
0
67
0
12
0
0
0
0
12
0
0
% S
% Thr:
0
0
0
12
0
0
0
67
0
12
12
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _