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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HNRPDL All Species: 11.21
Human Site: T181 Identified Species: 22.42
UniProt: O14979 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14979 NP_112740.1 420 46438 T181 V V D C T I K T D P V T G R S
Chimpanzee Pan troglodytes XP_001142289 401 44337 T181 V V D C T I K T D P V T G R S
Rhesus Macaque Macaca mulatta Q28521 320 34202 E117 G G I K E D T E E H H L R D Y
Dog Lupus familis XP_534176 420 46352 T181 V V D C T I K T D P V T G R S
Cat Felis silvestris
Mouse Mus musculus Q9Z130 301 33540 L98 E H K L D G K L I D P K R A K
Rat Rattus norvegicus Q3SWU3 322 35276 G118 L K E H K L D G K L I D P K R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512535 214 23768 S11 G G L S W D T S K K D L T E Y
Chicken Gallus gallus Q5ZI72 301 33425 K98 K E H K L D G K L I D P K R A
Frog Xenopus laevis Q7ZX83 293 32595 K90 V L E T N E H K L D G K L I D
Zebra Danio Brachydanio rerio NP_998557 296 33235 H93 R V L E L T E H K L D G K L I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22037 346 36325 S143 K Y G T V T K S E I I L D K A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q99383 534 59631 K192 V T D L K I M K D P A T G R S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.2 22.8 98.8 N.A. 71.4 70.2 N.A. 50.9 67.8 60.7 57.8 N.A. N.A. N.A. 22.8 N.A.
Protein Similarity: 100 95.2 37.1 99 N.A. 71.4 72.6 N.A. 50.9 69.7 64.7 64.2 N.A. N.A. N.A. 36.4 N.A.
P-Site Identity: 100 100 0 100 N.A. 6.6 0 N.A. 0 6.6 6.6 6.6 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 100 6.6 100 N.A. 6.6 33.3 N.A. 6.6 13.3 20 13.3 N.A. N.A. N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 38.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 60 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 9 0 0 9 17 % A
% Cys: 0 0 0 25 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 34 0 9 25 9 0 34 17 25 9 9 9 9 % D
% Glu: 9 9 17 9 9 9 9 9 17 0 0 0 0 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 17 17 9 0 0 9 9 9 0 0 9 9 34 0 0 % G
% His: 0 9 9 9 0 0 9 9 0 9 9 0 0 0 0 % H
% Ile: 0 0 9 0 0 34 0 0 9 17 17 0 0 9 9 % I
% Lys: 17 9 9 17 17 0 42 25 25 9 0 17 17 17 9 % K
% Leu: 9 9 17 17 17 9 0 9 17 17 0 25 9 9 0 % L
% Met: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 34 9 9 9 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 9 0 0 0 0 0 0 0 0 0 0 0 17 42 9 % R
% Ser: 0 0 0 9 0 0 0 17 0 0 0 0 0 0 34 % S
% Thr: 0 9 0 17 25 17 17 25 0 0 0 34 9 0 0 % T
% Val: 42 34 0 0 9 0 0 0 0 0 25 0 0 0 0 % V
% Trp: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 17 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _