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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XPO1
All Species:
31.82
Human Site:
S395
Identified Species:
63.64
UniProt:
O14980
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14980
NP_003391.1
1071
123386
S395
T
S
A
S
P
L
L
S
G
S
Q
H
F
D
V
Chimpanzee
Pan troglodytes
XP_001161222
1071
123367
S395
T
S
A
S
P
L
L
S
G
S
Q
H
F
D
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531839
1071
123123
S395
T
S
A
S
P
L
L
S
G
S
Q
H
F
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6P5F9
1071
123074
S395
T
S
A
S
P
L
L
S
G
S
Q
H
F
D
I
Rat
Rattus norvegicus
Q80U96
1071
123020
S395
T
S
A
S
P
L
L
S
G
S
Q
H
F
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512501
1059
121040
S383
T
S
A
S
P
L
L
S
G
S
Q
H
F
D
V
Chicken
Gallus gallus
XP_001231648
1071
123138
S395
T
S
A
S
P
L
L
S
G
S
Q
H
F
D
V
Frog
Xenopus laevis
NP_001083734
1071
123149
S395
T
S
A
S
P
L
L
S
G
S
Q
H
F
D
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9TVM2
1063
122781
R391
P
T
L
E
S
T
K
R
Q
Q
V
Y
P
R
R
Honey Bee
Apis mellifera
XP_396469
1062
122406
V389
S
P
T
P
L
F
V
V
K
N
I
T
L
P
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780879
1068
122315
L390
S
T
P
S
S
P
L
L
L
G
S
A
N
N
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P30822
1084
124086
L388
P
A
T
E
M
S
P
L
I
Q
L
S
V
G
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
98.8
N.A.
98
97.8
N.A.
95.5
98.5
97
N.A.
N.A.
70.7
76.4
N.A.
81
Protein Similarity:
100
100
N.A.
99.2
N.A.
98.7
98.7
N.A.
96.1
99.1
98.4
N.A.
N.A.
83
86.9
N.A.
89.5
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
100
100
100
N.A.
N.A.
0
0
N.A.
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
100
N.A.
N.A.
13.3
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
47.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
67.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
67
0
0
0
0
0
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
67
0
% D
% Glu:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
67
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
67
9
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
67
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
17
% I
% Lys:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% K
% Leu:
0
0
9
0
9
67
75
17
9
0
9
0
9
0
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
0
0
9
9
0
% N
% Pro:
17
9
9
9
67
9
9
0
0
0
0
0
9
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
9
17
67
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
9
0
0
0
0
0
9
9
% R
% Ser:
17
67
0
75
17
9
0
67
0
67
9
9
0
0
25
% S
% Thr:
67
17
17
0
0
9
0
0
0
0
0
9
0
0
0
% T
% Val:
0
0
0
0
0
0
9
9
0
0
9
0
9
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _