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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIP5K1B All Species: 32.73
Human Site: S67 Identified Species: 80
UniProt: O14986 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14986 NP_003549.1 540 61036 S67 V E S V F L P S E G S N L T P
Chimpanzee Pan troglodytes XP_001137042 540 60994 S67 V E S V F L P S E G S N L T P
Rhesus Macaque Macaca mulatta XP_001088891 535 60821 S65 V F L P S E G S N L T P A H H
Dog Lupus familis XP_533533 740 82433 S84 V E S V F L P S E G S N L T P
Cat Felis silvestris
Mouse Mus musculus P70181 539 60785 S67 V E S V F L P S E G S N L T P
Rat Rattus norvegicus Q5CZZ9 539 60715 S67 V E S V F L P S E G S N L T P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505902 612 68141 S67 V E S V F L P S E G S N L T P
Chicken Gallus gallus Q5ZJ58 540 60700 S67 V E S V F L P S E G S N L T P
Frog Xenopus laevis NP_001085811 537 60699 S67 V E S V F L P S E G S N L T P
Zebra Danio Brachydanio rerio Q6IQE1 416 47361
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 95.7 70.5 N.A. 96.3 95.7 N.A. 79.5 86.6 81.4 25.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 95.7 72 N.A. 97.5 97 N.A. 83.6 93.5 89.2 41.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 13.3 100 N.A. 100 100 N.A. 100 100 100 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 20 100 N.A. 100 100 N.A. 100 100 100 0 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 80 0 0 0 10 0 0 80 0 0 0 0 0 0 % E
% Phe: 0 10 0 0 80 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 10 0 0 80 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 10 0 0 80 0 0 0 10 0 0 80 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 10 0 0 80 0 0 0 % N
% Pro: 0 0 0 10 0 0 80 0 0 0 0 10 0 0 80 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 80 0 10 0 0 90 0 0 80 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 10 0 0 80 0 % T
% Val: 90 0 0 80 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _