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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SYN3 All Species: 21.82
Human Site: S484 Identified Species: 53.33
UniProt: O14994 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14994 NP_003481.3 580 63303 S484 Q Q Q R S P G S P Q L S R A S
Chimpanzee Pan troglodytes XP_515096 579 63181 S483 Q Q Q R S P G S P Q L S R A S
Rhesus Macaque Macaca mulatta XP_001086745 582 63133 S486 P G P S L P P S S S S S S S S
Dog Lupus familis XP_850873 579 63100 S483 P Q Q R S P G S P Q L S R A S
Cat Felis silvestris
Mouse Mus musculus Q8JZP2 579 63326 S483 Q Q Q R S P G S P Q L S R A S
Rat Rattus norvegicus O70441 579 63330 S483 Q Q Q R S P G S P Q L S R A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510451 589 64300 Q493 Q R S P G S P Q Q S R A A S G
Chicken Gallus gallus
Frog Xenopus laevis NP_001079204 580 63774 S484 W L P T D T T S R N S P Q L P
Zebra Danio Brachydanio rerio NP_001119909 670 72335 G573 A P Q P A P Q G S P R P P T T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24546 1025 107509 S709 S K S G S A A S I H T S S S S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 60.6 93.9 N.A. 92.4 92 N.A. 74.8 N.A. 68 52.8 N.A. 27.1 N.A. N.A. N.A.
Protein Similarity: 100 99.6 74.2 95.5 N.A. 95.1 95.3 N.A. 82.8 N.A. 79.1 65.9 N.A. 37.7 N.A. N.A. N.A.
P-Site Identity: 100 100 26.6 93.3 N.A. 100 100 N.A. 6.6 N.A. 6.6 13.3 N.A. 26.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 33.3 93.3 N.A. 100 100 N.A. 26.6 N.A. 13.3 26.6 N.A. 40 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 10 10 10 0 0 0 0 10 10 50 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 10 10 0 50 10 0 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 0 0 10 0 0 0 0 0 50 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % N
% Pro: 20 10 20 20 0 70 20 0 50 10 0 20 10 0 10 % P
% Gln: 50 50 60 0 0 0 10 10 10 50 0 0 10 0 0 % Q
% Arg: 0 10 0 50 0 0 0 0 10 0 20 0 50 0 0 % R
% Ser: 10 0 20 10 60 10 0 80 20 20 20 70 20 30 70 % S
% Thr: 0 0 0 10 0 10 10 0 0 0 10 0 0 10 10 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _