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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYN3
All Species:
15.76
Human Site:
S508
Identified Species:
38.52
UniProt:
O14994
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14994
NP_003481.3
580
63303
S508
K
P
G
A
T
L
A
S
Q
P
R
P
P
V
Q
Chimpanzee
Pan troglodytes
XP_515096
579
63181
S507
K
P
G
A
T
L
T
S
Q
P
R
P
P
V
Q
Rhesus Macaque
Macaca mulatta
XP_001086745
582
63133
A510
G
P
T
T
H
G
D
A
P
S
S
S
S
S
L
Dog
Lupus familis
XP_850873
579
63100
S507
K
P
G
A
L
L
T
S
Q
P
R
P
P
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8JZP2
579
63326
S507
K
P
S
A
S
L
S
S
H
N
R
P
P
V
Q
Rat
Rattus norvegicus
O70441
579
63330
S507
K
P
T
A
S
L
S
S
H
T
R
P
P
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510451
589
64300
P517
G
S
L
P
P
S
Q
P
R
P
P
A
Q
G
R
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079204
580
63774
S508
S
Q
T
P
K
S
V
S
P
Q
P
S
R
P
P
Zebra Danio
Brachydanio rerio
NP_001119909
670
72335
R597
Q
G
G
P
G
G
T
R
P
P
L
Q
Q
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24546
1025
107509
A733
R
I
N
R
N
G
N
A
I
Q
S
P
P
P
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
60.6
93.9
N.A.
92.4
92
N.A.
74.8
N.A.
68
52.8
N.A.
27.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
74.2
95.5
N.A.
95.1
95.3
N.A.
82.8
N.A.
79.1
65.9
N.A.
37.7
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
6.6
86.6
N.A.
66.6
66.6
N.A.
6.6
N.A.
6.6
13.3
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
13.3
86.6
N.A.
80
80
N.A.
20
N.A.
6.6
20
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
50
0
0
10
20
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
20
10
40
0
10
30
0
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
10
0
0
0
20
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
50
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
0
10
0
10
50
0
0
0
0
10
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
10
0
10
0
0
10
0
0
0
0
0
% N
% Pro:
0
60
0
30
10
0
0
10
30
50
20
60
60
20
30
% P
% Gln:
10
10
0
0
0
0
10
0
30
20
0
10
20
0
50
% Q
% Arg:
10
0
0
10
0
0
0
10
10
0
50
0
10
0
10
% R
% Ser:
10
10
10
0
20
20
20
60
0
10
20
20
10
10
0
% S
% Thr:
0
0
30
10
20
0
30
0
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
0
0
50
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _