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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGEF10
All Species:
8.48
Human Site:
S460
Identified Species:
37.33
UniProt:
O15013
Number Species:
5
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15013
NP_055444.2
1369
151612
S460
E
M
E
P
K
V
L
S
E
R
K
L
K
T
V
Chimpanzee
Pan troglodytes
XP_528056
1767
194241
S857
E
M
E
P
K
V
L
S
E
R
K
L
K
T
V
Rhesus Macaque
Macaca mulatta
XP_001089473
1283
140716
C448
F
L
K
R
R
Q
V
C
S
P
D
R
V
T
L
Dog
Lupus familis
XP_851867
1248
137729
V441
E
G
L
S
Q
Q
Q
V
V
R
R
Y
I
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8C033
1345
147927
F444
D
R
K
L
R
M
V
F
Y
R
V
K
E
I
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665240
1407
155582
S512
E
I
E
P
R
L
L
S
D
R
K
R
K
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.4
42
72.6
N.A.
79.1
N.A.
N.A.
N.A.
N.A.
N.A.
57.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
75.4
58.2
79
N.A.
86.7
N.A.
N.A.
N.A.
N.A.
N.A.
72.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
13.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
40
26.6
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% C
% Asp:
17
0
0
0
0
0
0
0
17
0
17
0
0
0
0
% D
% Glu:
67
0
50
0
0
0
0
0
34
0
0
0
17
0
0
% E
% Phe:
17
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% F
% Gly:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
17
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
17
0
0
0
0
0
0
0
0
0
0
17
17
0
% I
% Lys:
0
0
34
0
34
0
0
0
0
0
50
17
50
0
0
% K
% Leu:
0
17
17
17
0
17
50
0
0
0
0
34
0
17
34
% L
% Met:
0
34
0
0
0
17
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
50
0
0
0
0
0
17
0
0
0
0
0
% P
% Gln:
0
0
0
0
17
34
17
0
0
0
0
0
0
0
0
% Q
% Arg:
0
17
0
17
50
0
0
0
0
84
17
34
0
0
0
% R
% Ser:
0
0
0
17
0
0
0
50
17
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% T
% Val:
0
0
0
0
0
34
34
17
17
0
17
0
17
17
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
17
0
0
17
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _