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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLXNB2
All Species:
4.24
Human Site:
Y419
Identified Species:
7.78
UniProt:
O15031
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15031
NP_036533.2
1838
205127
Y419
D
G
R
I
L
K
V
Y
L
T
P
D
G
T
S
Chimpanzee
Pan troglodytes
XP_001136153
1893
212376
R456
S
G
K
L
K
K
I
R
V
D
G
P
R
G
N
Rhesus Macaque
Macaca mulatta
XP_001116282
1822
203562
A405
L
T
A
V
T
V
T
A
E
N
N
H
T
V
A
Dog
Lupus familis
XP_531689
1868
207916
R421
D
G
R
V
L
K
V
R
P
G
A
A
A
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9QY40
1892
207231
F404
Q
G
Q
L
H
K
V
F
L
N
S
S
H
G
Q
Rat
Rattus norvegicus
NP_001101576
1841
205931
Y421
D
G
R
I
L
K
V
Y
L
A
P
D
G
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517911
892
98588
Chicken
Gallus gallus
XP_423623
1854
210302
K441
T
S
D
G
K
I
L
K
V
F
L
S
S
T
V
Frog
Xenopus laevis
NP_001088457
1886
212406
L452
S
G
R
M
K
K
I
L
V
D
L
S
A
S
S
Zebra Danio
Brachydanio rerio
Q6BEA0
1903
213774
R467
G
G
R
L
K
K
I
R
V
D
G
P
T
Y
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4A7
2051
231661
L487
M
G
V
I
K
K
V
L
L
S
G
Q
S
P
G
Honey Bee
Apis mellifera
XP_395735
1939
217009
L468
D
G
V
L
K
K
V
L
L
S
G
N
E
A
F
Nematode Worm
Caenorhab. elegans
O45657
1766
195762
H399
V
M
F
K
W
D
E
H
H
S
N
Q
L
E
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.1
95.6
87.5
N.A.
40.8
88
N.A.
32.7
66.8
34.6
33.5
N.A.
29.6
34.4
25.8
N.A.
Protein Similarity:
100
53.2
97
91.5
N.A.
56.4
93.6
N.A.
38.6
78.6
53.1
53
N.A.
48.3
52.5
44.3
N.A.
P-Site Identity:
100
13.3
0
40
N.A.
26.6
93.3
N.A.
0
6.6
26.6
20
N.A.
33.3
33.3
0
N.A.
P-Site Similarity:
100
46.6
13.3
46.6
N.A.
46.6
93.3
N.A.
0
20
53.3
40
N.A.
40
53.3
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
8
0
8
8
8
16
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
31
0
8
0
0
8
0
0
0
24
0
16
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
8
0
0
0
8
8
8
% E
% Phe:
0
0
8
0
0
0
0
8
0
8
0
0
0
0
8
% F
% Gly:
8
70
0
8
0
0
0
0
0
8
31
0
16
24
24
% G
% His:
0
0
0
0
8
0
0
8
8
0
0
8
8
0
0
% H
% Ile:
0
0
0
24
0
8
24
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
8
47
70
0
8
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
31
24
0
8
24
39
0
16
0
8
0
0
% L
% Met:
8
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
16
16
8
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
16
16
0
8
0
% P
% Gln:
8
0
8
0
0
0
0
0
0
0
0
16
0
0
8
% Q
% Arg:
0
0
39
0
0
0
0
24
0
0
0
0
8
0
0
% R
% Ser:
16
8
0
0
0
0
0
0
0
24
8
24
16
8
24
% S
% Thr:
8
8
0
0
8
0
8
0
0
8
0
0
16
24
0
% T
% Val:
8
0
16
16
0
8
47
0
31
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
16
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _