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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA0317 All Species: 29.09
Human Site: S475 Identified Species: 64
UniProt: O15033 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15033 NP_001034568.1 823 94223 S475 R H A L L E S S L K A T R N F
Chimpanzee Pan troglodytes XP_001156986 823 94250 S475 R H A L L E S S L K A T R N F
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_547907 770 88243 T469 C K A L F D T T N Q L F T R F
Cat Felis silvestris
Mouse Mus musculus Q8CHG5 823 94180 S475 R H A L L E S S L K A T R N F
Rat Rattus norvegicus Q62940 887 102376 S542 R A N I L E D S Y R R I M G V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421269 823 94304 S475 R H S L L E S S F K A T R N F
Frog Xenopus laevis Q6DCL5 944 106566 S601 R D S I F R S S C E V V F K S
Zebra Danio Brachydanio rerio A9JRZ0 765 87445 E465 W L Y L L S H E M L N P Y Y G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVI3 1007 114856 S663 R T S I L E D S Y R I I S S V
Honey Bee Apis mellifera XP_001121820 910 102565 S582 R D K L L E S S M K S T K G F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001199840 953 107716 S602 R H N L L E S S M K A T K S L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 N.A. 91.1 N.A. 97.2 25.1 N.A. N.A. 91.3 23 22.9 N.A. 23.5 39.2 N.A. 37
Protein Similarity: 100 99.7 N.A. 92.5 N.A. 99.1 42.7 N.A. N.A. 97 41 40.2 N.A. 40.2 54.1 N.A. 55.6
P-Site Identity: 100 100 N.A. 20 N.A. 100 26.6 N.A. N.A. 86.6 20 13.3 N.A. 26.6 60 N.A. 66.6
P-Site Similarity: 100 100 N.A. 46.6 N.A. 100 40 N.A. N.A. 93.3 40 20 N.A. 53.3 80 N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 37 0 0 0 0 0 0 0 46 0 0 0 0 % A
% Cys: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 0 19 0 0 0 10 19 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 73 0 10 0 10 0 0 0 0 0 % E
% Phe: 0 0 0 0 19 0 0 0 10 0 0 10 10 0 55 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 19 10 % G
% His: 0 46 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 28 0 0 0 0 0 0 10 19 0 0 0 % I
% Lys: 0 10 10 0 0 0 0 0 0 55 0 0 19 10 0 % K
% Leu: 0 10 0 73 82 0 0 0 28 10 10 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 28 0 0 0 10 0 0 % M
% Asn: 0 0 19 0 0 0 0 0 10 0 10 0 0 37 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Q
% Arg: 82 0 0 0 0 10 0 0 0 19 10 0 37 10 0 % R
% Ser: 0 0 28 0 0 10 64 82 0 0 10 0 10 19 10 % S
% Thr: 0 10 0 0 0 0 10 10 0 0 0 55 10 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 19 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 19 0 0 0 10 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _