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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEMA3E All Species: 15.45
Human Site: S700 Identified Species: 30.91
UniProt: O15041 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15041 NP_036563.1 775 89228 S700 R M P C P A Q S S I S Q G A K
Chimpanzee Pan troglodytes XP_527803 775 89179 S700 R M P C P A Q S S I S Q G A K
Rhesus Macaque Macaca mulatta XP_001096722 734 84680 N656 S K T K E M S N S M T P S Q K
Dog Lupus familis XP_540506 512 58572 E438 E N N S T L L E C T P R S L Q
Cat Felis silvestris
Mouse Mus musculus P70275 775 89485 S700 K M P C P P L S G M S Q G T K
Rat Rattus norvegicus Q63548 772 88790 S694 S K T K E M S S S M T P S Q K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506080 604 69966 S530 M P C P V Q R S V S Q P P R P
Chicken Gallus gallus O42237 785 90960 S704 K M P C P M Q S N I P Q V S K
Frog Xenopus laevis NP_001079324 774 89301 N696 H K H K E P S N S M S P T Q K
Zebra Danio Brachydanio rerio Q9W686 778 88886 T687 L H R D P P D T N D P A N G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24322 850 95478 R745 R D N F G T L R S H Q V M G D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q17330 712 78063 S638 A R L T R H D S L T T A T K V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 46.9 58.7 N.A. 90 48.3 N.A. 64.5 80.1 48 45.8 N.A. 27.2 N.A. 27.1 N.A.
Protein Similarity: 100 99.8 66.9 61.6 N.A. 95.2 67.6 N.A. 71.4 88.6 68.2 64.2 N.A. 46 N.A. 46.7 N.A.
P-Site Identity: 100 100 13.3 0 N.A. 60 20 N.A. 6.6 60 20 13.3 N.A. 13.3 N.A. 6.6 N.A.
P-Site Similarity: 100 100 33.3 13.3 N.A. 73.3 33.3 N.A. 13.3 80 33.3 26.6 N.A. 13.3 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 17 0 0 0 0 0 17 0 17 0 % A
% Cys: 0 0 9 34 0 0 0 0 9 0 0 0 0 0 0 % C
% Asp: 0 9 0 9 0 0 17 0 0 9 0 0 0 0 9 % D
% Glu: 9 0 0 0 25 0 0 9 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 9 0 0 0 9 0 0 0 25 17 0 % G
% His: 9 9 9 0 0 9 0 0 0 9 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 25 0 0 0 0 0 % I
% Lys: 17 25 0 25 0 0 0 0 0 0 0 0 0 9 67 % K
% Leu: 9 0 9 0 0 9 25 0 9 0 0 0 0 9 0 % L
% Met: 9 34 0 0 0 25 0 0 0 34 0 0 9 0 0 % M
% Asn: 0 9 17 0 0 0 0 17 17 0 0 0 9 0 0 % N
% Pro: 0 9 34 9 42 25 0 0 0 0 25 34 9 0 9 % P
% Gln: 0 0 0 0 0 9 25 0 0 0 17 34 0 25 9 % Q
% Arg: 25 9 9 0 9 0 9 9 0 0 0 9 0 9 0 % R
% Ser: 17 0 0 9 0 0 25 59 50 9 34 0 25 9 0 % S
% Thr: 0 0 17 9 9 9 0 9 0 17 25 0 17 9 0 % T
% Val: 0 0 0 0 9 0 0 0 9 0 0 9 9 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _