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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEMA3E
All Species:
13.64
Human Site:
Y118
Identified Species:
27.27
UniProt:
O15041
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15041
NP_036563.1
775
89228
Y118
D
A
G
E
C
A
N
Y
V
R
V
L
H
H
Y
Chimpanzee
Pan troglodytes
XP_527803
775
89179
Y118
D
A
G
E
C
A
N
Y
V
R
V
L
H
H
Y
Rhesus Macaque
Macaca mulatta
XP_001096722
734
84680
N115
I
G
H
H
P
E
D
N
I
F
K
L
E
N
S
Dog
Lupus familis
XP_540506
512
58572
Cat
Felis silvestris
Mouse
Mus musculus
P70275
775
89485
Y118
D
A
N
E
C
A
N
Y
I
R
V
L
H
H
Y
Rat
Rattus norvegicus
Q63548
772
88790
F117
I
L
K
E
C
A
N
F
I
K
V
L
K
A
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506080
604
69966
Chicken
Gallus gallus
O42237
785
90960
Y122
D
A
D
E
C
A
N
Y
V
R
V
L
H
R
Y
Frog
Xenopus laevis
NP_001079324
774
89301
I118
V
K
E
C
A
N
F
I
K
V
L
K
A
Y
N
Zebra Danio
Brachydanio rerio
Q9W686
778
88886
N118
D
V
Q
K
E
C
A
N
F
I
K
V
L
Q
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24322
850
95478
Y139
Y
I
I
S
D
S
N
Y
T
L
E
A
T
K
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17330
712
78063
D108
M
K
G
K
S
K
T
D
C
Q
N
Y
I
R
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
46.9
58.7
N.A.
90
48.3
N.A.
64.5
80.1
48
45.8
N.A.
27.2
N.A.
27.1
N.A.
Protein Similarity:
100
99.8
66.9
61.6
N.A.
95.2
67.6
N.A.
71.4
88.6
68.2
64.2
N.A.
46
N.A.
46.7
N.A.
P-Site Identity:
100
100
6.6
0
N.A.
86.6
46.6
N.A.
0
86.6
0
6.6
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
100
26.6
0
N.A.
93.3
66.6
N.A.
0
86.6
13.3
20
N.A.
20
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
0
0
9
42
9
0
0
0
0
9
9
9
0
% A
% Cys:
0
0
0
9
42
9
0
0
9
0
0
0
0
0
0
% C
% Asp:
42
0
9
0
9
0
9
9
0
0
0
0
0
0
0
% D
% Glu:
0
0
9
42
9
9
0
0
0
0
9
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
9
9
9
9
0
0
0
0
0
% F
% Gly:
0
9
25
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
9
9
0
0
0
0
0
0
0
0
34
25
0
% H
% Ile:
17
9
9
0
0
0
0
9
25
9
0
0
9
0
0
% I
% Lys:
0
17
9
17
0
9
0
0
9
9
17
9
9
9
0
% K
% Leu:
0
9
0
0
0
0
0
0
0
9
9
50
9
0
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
9
50
17
0
0
9
0
0
9
17
% N
% Pro:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
9
% P
% Gln:
0
0
9
0
0
0
0
0
0
9
0
0
0
9
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
34
0
0
0
17
0
% R
% Ser:
0
0
0
9
9
9
0
0
0
0
0
0
0
0
9
% S
% Thr:
0
0
0
0
0
0
9
0
9
0
0
0
9
0
0
% T
% Val:
9
9
0
0
0
0
0
0
25
9
42
9
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
42
0
0
0
9
0
9
42
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _