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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SR140 All Species: 14.24
Human Site: S272 Identified Species: 44.76
UniProt: O15042 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15042 NP_001073884.1 1029 118292 S272 S H D V G D P S T T N L Y L G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001107114 1096 125607 S339 S H D V G D P S T T N L Y L G
Dog Lupus familis XP_534297 1258 143594 S501 S H D V G D P S T T N L Y L G
Cat Felis silvestris
Mouse Mus musculus Q6NV83 1029 118227 S272 S H D V G D P S T T N L Y L G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611535 957 108434 Y266 R N C G F V A Y M S R K D A E
Honey Bee Apis mellifera XP_397019 601 69866
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001179024 1012 117424 P263 K E F V Q Y G P L A S V K I M
Poplar Tree Populus trichocarpa XP_002324341 955 108033 I263 V Y E Y E L K I G W G K S V A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 93.6 81.7 N.A. 98.9 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 40.2 27.1 N.A. 51.1
Protein Similarity: 100 N.A. 93.6 81.7 N.A. 99.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 57 38.7 N.A. 68.4
P-Site Identity: 100 N.A. 100 100 N.A. 100 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 0 0 N.A. 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 13.3 0 N.A. 26.6
Percent
Protein Identity: 28.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 45.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 20 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 13 0 0 13 0 0 0 13 13 % A
% Cys: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 50 0 0 50 0 0 0 0 0 0 13 0 0 % D
% Glu: 0 13 13 0 13 0 0 0 0 0 0 0 0 0 13 % E
% Phe: 0 0 13 0 13 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 13 50 0 13 0 13 0 13 0 0 0 50 % G
% His: 0 50 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 13 0 0 0 0 0 13 0 % I
% Lys: 13 0 0 0 0 0 13 0 0 0 0 25 13 0 0 % K
% Leu: 0 0 0 0 0 13 0 0 13 0 0 50 0 50 0 % L
% Met: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 13 % M
% Asn: 0 13 0 0 0 0 0 0 0 0 50 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 50 13 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 13 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % R
% Ser: 50 0 0 0 0 0 0 50 0 13 13 0 13 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 50 50 0 0 0 0 0 % T
% Val: 13 0 0 63 0 13 0 0 0 0 0 13 0 13 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 % W
% Tyr: 0 13 0 13 0 13 0 13 0 0 0 0 50 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _