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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1A
All Species:
7.27
Human Site:
S1196
Identified Species:
12.31
UniProt:
O15047
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15047
NP_055527.1
1707
186034
S1196
A
K
F
P
G
P
A
S
R
K
A
P
R
G
V
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
S1196
A
K
F
P
G
P
A
S
R
K
A
P
R
G
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848999
1330
145541
E875
R
K
V
P
R
T
V
E
R
T
I
R
N
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
T1401
S
T
E
T
V
P
A
T
P
G
G
E
P
P
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506028
1287
141359
P832
R
T
T
T
L
S
P
P
H
P
P
A
P
R
E
Chicken
Gallus gallus
Q5F3P8
2008
223067
K1358
P
L
P
S
T
P
G
K
E
E
S
V
V
P
P
Frog
Xenopus laevis
Q66J90
1938
216239
Q1390
S
P
F
S
Y
L
S
Q
S
P
G
I
I
N
S
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
D1269
T
P
G
R
D
L
M
D
R
A
R
G
L
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
N1146
K
N
N
N
S
P
R
N
K
N
D
E
T
R
K
Honey Bee
Apis mellifera
XP_395451
1406
159180
E951
N
D
E
P
I
L
K
E
S
E
K
I
E
M
F
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
E1052
R
P
L
P
E
P
V
E
T
S
G
P
I
I
G
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
S1445
T
Q
E
S
E
T
P
S
K
V
T
L
D
K
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38827
1080
123894
S625
R
N
L
K
R
H
N
S
L
A
L
D
H
T
S
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
V858
E
S
V
T
P
T
G
V
E
A
P
L
N
G
L
Conservation
Percent
Protein Identity:
100
99.5
N.A.
73.2
N.A.
37
N.A.
N.A.
27.7
34.5
34.1
36.7
N.A.
25.6
24.6
20.9
23.7
Protein Similarity:
100
99.5
N.A.
74.7
N.A.
49.5
N.A.
N.A.
38.7
47.5
48.6
50.7
N.A.
41.3
39.6
35.8
39.2
P-Site Identity:
100
100
N.A.
20
N.A.
13.3
N.A.
N.A.
0
6.6
6.6
13.3
N.A.
6.6
6.6
20
6.6
P-Site Similarity:
100
100
N.A.
20
N.A.
33.3
N.A.
N.A.
0
20
20
13.3
N.A.
20
13.3
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.8
36.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
0
0
22
0
0
22
15
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
8
0
0
8
0
0
8
8
8
0
0
% D
% Glu:
8
0
22
0
15
0
0
22
15
15
0
15
8
0
8
% E
% Phe:
0
0
22
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
8
0
15
0
15
0
0
8
22
8
0
29
8
% G
% His:
0
0
0
0
0
8
0
0
8
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
8
15
15
8
0
% I
% Lys:
8
22
0
8
0
0
8
8
15
15
8
0
0
8
15
% K
% Leu:
0
8
15
0
8
22
0
0
8
0
8
15
8
8
15
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% M
% Asn:
8
15
8
8
0
0
8
8
0
8
0
0
15
8
0
% N
% Pro:
8
22
8
36
8
43
15
8
8
15
15
22
15
15
22
% P
% Gln:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
29
0
0
8
15
0
8
0
29
0
8
8
15
15
0
% R
% Ser:
15
8
0
22
8
8
8
29
15
8
8
0
0
0
15
% S
% Thr:
15
15
8
22
8
22
0
8
8
8
8
0
8
8
0
% T
% Val:
0
0
15
0
8
0
15
8
0
8
0
8
8
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _