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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1A
All Species:
7.88
Human Site:
S1396
Identified Species:
13.33
UniProt:
O15047
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15047
NP_055527.1
1707
186034
S1396
L
R
R
R
S
L
R
S
H
A
R
R
R
R
P
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
S1396
L
R
R
R
S
L
R
S
H
A
R
R
R
R
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848999
1330
145541
E1039
P
P
S
P
P
S
F
E
P
R
S
E
F
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
R1668
W
R
R
P
P
K
K
R
H
E
D
L
V
A
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506028
1287
141359
F996
L
F
R
P
R
S
E
F
E
E
M
T
I
L
Y
Chicken
Gallus gallus
Q5F3P8
2008
223067
R1684
E
A
H
A
K
P
K
R
Q
W
R
R
Q
K
K
Frog
Xenopus laevis
Q66J90
1938
216239
S1617
K
H
K
K
S
R
N
S
R
L
N
K
L
Y
D
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
S1479
N
Q
Y
P
D
L
P
S
E
S
I
K
E
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
W1315
M
T
P
N
G
D
E
W
P
D
L
A
H
K
N
Honey Bee
Apis mellifera
XP_395451
1406
159180
D1115
E
F
L
T
R
G
I
D
A
E
D
V
E
Y
L
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
D1216
G
D
C
E
D
L
P
D
L
E
D
Q
W
Y
L
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
D1623
L
E
P
L
A
I
V
D
H
T
Y
C
Q
K
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38827
1080
123894
T789
S
T
Y
T
P
T
V
T
P
E
T
S
A
A
L
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
R1022
P
D
A
Q
R
L
Q
R
K
F
G
T
A
K
L
Conservation
Percent
Protein Identity:
100
99.5
N.A.
73.2
N.A.
37
N.A.
N.A.
27.7
34.5
34.1
36.7
N.A.
25.6
24.6
20.9
23.7
Protein Similarity:
100
99.5
N.A.
74.7
N.A.
49.5
N.A.
N.A.
38.7
47.5
48.6
50.7
N.A.
41.3
39.6
35.8
39.2
P-Site Identity:
100
100
N.A.
0
N.A.
26.6
N.A.
N.A.
13.3
13.3
13.3
13.3
N.A.
0
0
6.6
20
P-Site Similarity:
100
100
N.A.
0
N.A.
33.3
N.A.
N.A.
13.3
33.3
33.3
33.3
N.A.
13.3
0
13.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.8
36.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
8
0
0
0
8
15
0
8
15
15
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
15
0
0
15
8
0
22
0
8
22
0
0
0
15
% D
% Glu:
15
8
0
8
0
0
15
8
15
36
0
8
15
15
0
% E
% Phe:
0
15
0
0
0
0
8
8
0
8
0
0
8
0
0
% F
% Gly:
8
0
0
0
8
8
0
0
0
0
8
0
0
0
0
% G
% His:
0
8
8
0
0
0
0
0
29
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
8
8
0
0
0
8
0
8
0
0
% I
% Lys:
8
0
8
8
8
8
15
0
8
0
0
15
0
29
8
% K
% Leu:
29
0
8
8
0
36
0
0
8
8
8
8
8
8
29
% L
% Met:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
8
0
0
8
0
0
8
0
0
0
8
0
0
0
8
% N
% Pro:
15
8
15
29
22
8
15
0
22
0
0
0
0
0
29
% P
% Gln:
0
8
0
8
0
0
8
0
8
0
0
8
15
0
8
% Q
% Arg:
0
22
29
15
22
8
15
22
8
8
22
22
15
15
0
% R
% Ser:
8
0
8
0
22
15
0
29
0
8
8
8
0
0
0
% S
% Thr:
0
15
0
15
0
8
0
8
0
8
8
15
0
0
0
% T
% Val:
0
0
0
0
0
0
15
0
0
0
0
8
8
0
0
% V
% Trp:
8
0
0
0
0
0
0
8
0
8
0
0
8
0
0
% W
% Tyr:
0
0
15
0
0
0
0
0
0
0
8
0
0
22
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _