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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1A
All Species:
19.39
Human Site:
S1419
Identified Species:
32.82
UniProt:
O15047
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15047
NP_055527.1
1707
186034
S1419
P
R
A
Y
E
P
R
S
E
F
E
Q
M
T
I
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
S1419
P
R
A
Y
E
P
R
S
E
F
E
Q
M
T
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848999
1330
145541
L1058
Y
D
I
W
N
S
G
L
D
L
E
D
M
G
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
S1692
Q
P
L
F
R
P
R
S
E
F
E
E
M
T
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506028
1287
141359
I1015
G
G
I
D
E
E
D
I
K
F
L
C
I
T
Y
Chicken
Gallus gallus
Q5F3P8
2008
223067
S1715
Q
P
Q
F
R
P
R
S
E
F
E
E
M
T
I
Frog
Xenopus laevis
Q66J90
1938
216239
S1645
R
A
M
F
K
P
R
S
E
F
E
E
M
T
I
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
S1550
R
P
S
F
M
P
R
S
D
F
E
E
M
T
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
D1335
C
D
M
Y
K
T
R
D
Q
N
E
E
M
V
I
Honey Bee
Apis mellifera
XP_395451
1406
159180
S1134
E
A
L
L
A
D
D
S
Q
G
Y
W
L
N
D
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
K1235
N
E
M
Q
S
E
V
K
S
A
D
E
L
P
W
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
V1663
I
N
N
L
I
P
E
V
K
Y
V
T
L
D
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38827
1080
123894
L808
W
Q
S
R
R
K
V
L
E
E
E
K
A
S
D
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
N1041
E
L
W
L
W
R
R
N
R
I
R
Q
L
N
S
Conservation
Percent
Protein Identity:
100
99.5
N.A.
73.2
N.A.
37
N.A.
N.A.
27.7
34.5
34.1
36.7
N.A.
25.6
24.6
20.9
23.7
Protein Similarity:
100
99.5
N.A.
74.7
N.A.
49.5
N.A.
N.A.
38.7
47.5
48.6
50.7
N.A.
41.3
39.6
35.8
39.2
P-Site Identity:
100
100
N.A.
13.3
N.A.
60
N.A.
N.A.
20
60
60
53.3
N.A.
33.3
6.6
0
6.6
P-Site Similarity:
100
100
N.A.
26.6
N.A.
73.3
N.A.
N.A.
33.3
73.3
80
80
N.A.
53.3
20
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.8
36.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
15
0
8
0
0
0
0
8
0
0
8
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
15
0
8
0
8
15
8
15
0
8
8
0
8
15
% D
% Glu:
15
8
0
0
22
15
8
0
43
8
65
43
0
0
0
% E
% Phe:
0
0
0
29
0
0
0
0
0
50
0
0
0
0
0
% F
% Gly:
8
8
0
0
0
0
8
0
0
8
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
15
0
8
0
0
8
0
8
0
0
8
0
50
% I
% Lys:
0
0
0
0
15
8
0
8
15
0
0
8
0
0
8
% K
% Leu:
0
8
15
22
0
0
0
15
0
8
8
0
29
0
0
% L
% Met:
0
0
22
0
8
0
0
0
0
0
0
0
58
0
0
% M
% Asn:
8
8
8
0
8
0
0
8
0
8
0
0
0
15
0
% N
% Pro:
15
22
0
0
0
50
0
0
0
0
0
0
0
8
0
% P
% Gln:
15
8
8
8
0
0
0
0
15
0
0
22
0
0
0
% Q
% Arg:
15
15
0
8
22
8
58
0
8
0
8
0
0
0
0
% R
% Ser:
0
0
15
0
8
8
0
50
8
0
0
0
0
8
8
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
0
8
0
50
0
% T
% Val:
0
0
0
0
0
0
15
8
0
0
8
0
0
8
0
% V
% Trp:
8
0
8
8
8
0
0
0
0
0
0
8
0
0
8
% W
% Tyr:
8
0
0
22
0
0
0
0
0
8
8
0
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _