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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1A
All Species:
6.36
Human Site:
S1555
Identified Species:
10.77
UniProt:
O15047
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15047
NP_055527.1
1707
186034
S1555
G
T
S
A
I
M
D
S
D
L
L
K
L
N
Q
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
S1555
G
T
S
A
I
M
D
S
D
L
L
K
L
N
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848999
1330
145541
L1193
L
K
F
R
K
K
K
L
R
F
G
R
S
R
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
F1827
Q
R
R
L
L
S
S
F
T
G
S
C
D
S
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506028
1287
141359
L1150
L
K
F
R
K
K
K
L
K
F
C
K
S
H
I
Chicken
Gallus gallus
Q5F3P8
2008
223067
F1850
Q
R
R
L
L
S
S
F
T
G
S
C
D
S
D
Frog
Xenopus laevis
Q66J90
1938
216239
F1780
Q
R
R
L
L
S
S
F
T
G
S
C
D
S
D
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
F1688
Q
R
R
L
L
S
S
F
S
C
D
S
D
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
S1474
G
I
S
R
E
A
R
S
N
Q
R
R
L
L
T
Honey Bee
Apis mellifera
XP_395451
1406
159180
L1269
L
K
F
R
K
K
Q
L
K
F
A
K
S
G
I
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
I1370
L
K
F
R
K
K
M
I
K
F
A
R
S
R
I
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
Q1804
R
R
F
I
A
V
L
Q
Q
Q
E
E
Q
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38827
1080
123894
A943
R
K
K
P
V
M
F
A
R
S
A
I
H
N
W
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
A1176
R
K
K
P
V
K
F
A
R
S
A
I
H
N
W
Conservation
Percent
Protein Identity:
100
99.5
N.A.
73.2
N.A.
37
N.A.
N.A.
27.7
34.5
34.1
36.7
N.A.
25.6
24.6
20.9
23.7
Protein Similarity:
100
99.5
N.A.
74.7
N.A.
49.5
N.A.
N.A.
38.7
47.5
48.6
50.7
N.A.
41.3
39.6
35.8
39.2
P-Site Identity:
100
100
N.A.
0
N.A.
0
N.A.
N.A.
6.6
0
0
0
N.A.
26.6
6.6
0
0
P-Site Similarity:
100
100
N.A.
6.6
N.A.
13.3
N.A.
N.A.
13.3
13.3
13.3
6.6
N.A.
40
6.6
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.8
36.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
8
8
0
15
0
0
29
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
8
22
0
0
0
% C
% Asp:
0
0
0
0
0
0
15
0
15
0
8
0
29
0
22
% D
% Glu:
0
0
0
0
8
0
0
0
0
0
8
8
0
0
0
% E
% Phe:
0
0
36
0
0
0
15
29
0
29
0
0
0
0
0
% F
% Gly:
22
0
0
0
0
0
0
0
0
22
8
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
15
8
0
% H
% Ile:
0
8
0
8
15
0
0
8
0
0
0
15
0
0
29
% I
% Lys:
0
43
15
0
29
36
15
0
22
0
0
29
0
0
0
% K
% Leu:
29
0
0
29
29
0
8
22
0
15
15
0
22
15
8
% L
% Met:
0
0
0
0
0
22
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
29
0
% N
% Pro:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
29
0
0
0
0
0
8
8
8
15
0
0
8
0
15
% Q
% Arg:
22
36
29
36
0
0
8
0
22
0
8
22
0
15
0
% R
% Ser:
0
0
22
0
0
29
29
22
8
15
22
8
29
22
8
% S
% Thr:
0
15
0
0
0
0
0
0
22
0
0
0
0
0
8
% T
% Val:
0
0
0
0
15
8
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _